Evidence map›Paper›PMID 39817749›Full record

ArticleMicrobiology spectrum2025

Association between the

Yasunobu Amari, Masahiro Hosonuma, Takuya Mizukami, Junya Isobe, Yuki Azetsu, Eiji Funayama, Yuki Maruyama, Toshiaki Tsurui, Kohei Tajima, Aya Sasaki and 16 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

26 authors.

Yasunobu AmariDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.ORCID 0009-0004-7645-8955
Masahiro HosonumaDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.ORCID 0000-0002-5861-7543
Takuya MizukamiDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Junya IsobeDepartment of Hospital Pharmaceutics, School of Pharmacy, Showa University Graduate School of Pharmacy, Shinagawa, Tokyo, Japan.
Yuki AzetsuPharmacological Research Center, Showa University, Shinagawa, Tokyo, Japan.
Eiji FunayamaDepartment of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology & Therapeutics, Showa University, Setagaya, Tokyo, Japan.
Yuki MaruyamaDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Toshiaki TsuruiDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Kohei TajimaDepartment of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology & Therapeutics, Showa University, Setagaya, Tokyo, Japan.
Aya SasakiDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Yoshitaka YamazakiPharmacological Research Center, Showa University, Shinagawa, Tokyo, Japan.
Ryota NakanoDepartment of Physiology, Showa University Graduate School of Pharmacy, Shinagawa, Tokyo, Japan.
Yutaka SanoDepartment of Orthopaedic Surgery, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
Atsushi IshidaDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Tatsuya NakanishiDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Seiji MochizukiDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Yuri YoshizawaDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Sumito KumagaiDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Sakiko YasuharaDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Kakei RyuDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Tatsunori OguchiDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Atsuo KuramasuDepartment of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology & Therapeutics, Showa University, Setagaya, Tokyo, Japan.
Kiyoshi YoshimuraDepartment of Clinical Immuno Oncology, Clinical Research Institute for Clinical Pharmacology & Therapeutics, Showa University, Setagaya, Tokyo, Japan.
Takehiko SambeDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.
Sei KobayashiDepartment of Otolaryngology, Showa University Fujigaoka Hospital, Yokohama, Kanagawa, Japan.
Naoki UchidaDepartment of Pharmacology, Showa University Graduate School of Medicine, Shinagawa, Tokyo, Japan.

Funding

Showa University
6 · The paper itself

Abstract

The concept of genome-microbiome interactions, in which the microenvironment determined by host genetic polymorphisms regulates the local microbiota, is important in the pathogenesis of human disease. In otolaryngology, the resident bacterial microbiota is reportedly altered in non-infectious ear diseases, such as otitis media pearls and exudative otitis media. We hypothesized that a single-nucleotide polymorphism in the ATP-binding cassette sub-family C member 11 ( IMPORTANCE: The

Indexed as

ATP-Binding Cassette TransportersCerumenEar CanalMicrobiotaPolymorphism, Single NucleotideAdultBacteriaCorynebacteriumFemaleHealthy VolunteersHumansMaleMiddle AgedYoung AdultABCC11 protein, humanATP-Binding Cassette TransportersABCC11ear canalgenome-microbiome interactionhuman microbiome

Identifiers

PMID39817749
PMCPMC11792512

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.