Evidence map›Paper›PMID 39817720›Full record

ArticleeLife2025

Target-agnostic identification of human antibodies to

Axelle Amen, Randy Yoo, Amanda Fabra-García, Judith Bolscher, William J R Stone, Isabelle Bally, Sebastián Dergan-Dylon, Iga Kucharska, Roos M de Jong, Marloes de Bruijni and 7 more

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Axelle Amen *CNRS, Université Grenoble Alpes, CEA, UMR5075, Institut de Biologie Structurale, Grenoble, France.ORCID https://orcid.org/0000-0002-0449-4445
Randy Yoo *Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada.ORCID https://orcid.org/0000-0002-6952-9039
Amanda Fabra-García *Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0001-6663-213X
Judith BolscherTropIQ Health Sciences, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0002-1898-6096
William J R StoneDepartment of Immunology and Infection, London School of Hygiene and Tropical Medicine, London, United Kingdom.ORCID https://orcid.org/0000-0002-6647-0166
Isabelle BallyCNRS, Université Grenoble Alpes, CEA, UMR5075, Institut de Biologie Structurale, Grenoble, France.
Sebastián Dergan-DylonCNRS, Université Grenoble Alpes, CEA, UMR5075, Institut de Biologie Structurale, Grenoble, France.
Iga KucharskaProgram in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada.
Roos M de JongDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.
Marloes de BruijniTropIQ Health Sciences, Nijmegen, Netherlands.
Teun BousemaDepartment of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0003-2666-094X
C Richter KingCenter for Vaccine Innovation and Access, PATH, Washington D.C., United States.
Randall S MacGillCenter for Vaccine Innovation and Access, PATH, Washington D.C., United States.ORCID https://orcid.org/0000-0002-4566-1481
Robert W SauerweinTropIQ Health Sciences, Nijmegen, Netherlands.
Jean-Philippe Julien *Program in Molecular Medicine, The Hospital for Sick Children Research Institute, Toronto, Canada.ORCID https://orcid.org/0000-0001-7602-3995
Pascal Poignard *CNRS, Université Grenoble Alpes, CEA, UMR5075, Institut de Biologie Structurale, Grenoble, France.ORCID https://orcid.org/0000-0002-0021-7192
Matthijs M Jore *Department of Medical Microbiology, Radboud University Medical Center, Nijmegen, Netherlands.ORCID https://orcid.org/0000-0002-0686-370X

Funding

X-ray Scattering Technology CoreP30GM133893 · NIGMS · BROOKHAVEN SCIENCE ASSOC-BROOKHAVEN LAB · PI Vivian Stojanoff · 2019 to 2026
$38.6M
User Training & OutreachP30GM138396 · NIGMS · UCHICAGO ARGONNE, LLC · PI ROBERT F. FISCHETTI, JANET L. SMITH · 2020 to 2026
$34.3M
ChimeraX -- Next Generation Visualization and Analysis Software for Multiscale ModelingR01GM129325 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI FERRIN, THOMAS E · 2018 to 2025
$5.2M
High-Speed High-Sensitivity Detector for X-ray Micro-Crystallography at GM/CA@APSS10OD012289 · OD · UNIVERSITY OF CHICAGO · PI FISCHETTI, ROBERT F. · 2014 to 2014
$2.0M
Bill and Melinda Gates Foundation OPP1108403CIHR 428410Nederlandse Organisatie voor Wetenschappelijk Onderzoek VIDI fellowship number 192.061NIGMS NIH HHS P30 GM133893NIGMS NIH HHS P30 GM138396NIGMS NIH HHS R01 GM129325NIH HHS S10 OD012289Wellcome TrustWellcome Trust 218676/Z/19/Z
6 · The paper itself

Abstract

Circulating sexual stages of

Indexed as

Antibodies, MonoclonalAntibodies, ProtozoanGlutamic AcidPlasmodium falciparumProtozoan ProteinsAnimalsAntigens, ProtozoanCross ReactionsHumansLife Cycle StagesMalaria, FalciparumAntibodies, MonoclonalAntibodies, ProtozoanAntigens, ProtozoanGlutamic AcidProtozoan Proteinsgametesgametocyteshomotypic interactionsimmunologyinfectious diseaseinflammationmicrobiologymonoclonal antibodyP. falciparumrepeat motiftransmission-blocking

Identifiers

PMID39817720
PMCPMC11737873

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.