Evidence map›Paper›PMID 39817528›Full record

ArticleJournal of the American Heart Association2025

Prognostic Impact of 1-Year Changes in Creatinine- and Cystatin C-Based Estimated Glomerular Filtration Rate After Stroke on 5-Year Outcomes: Insights From the Third China National Stroke Registry.

Yin Zhang, Yuesong Pan, Hongyi Yan, Xia Meng, Jinxi Lin, Mengxing Wang, Hao Li, Qin Xu, Pan Chen, Anxin Wang and 2 more

Abstract readMulticenter Study
In one paragraph

Article in Journal of the American Heart Association, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Yin ZhangDepartment of Nephrology Beijing Tiantan Hospital, Capital Medical University Beijing China.
Yuesong PanDepartment of Epidemiology and Health Statistics, School of Public Health Capital Medical University Beijing China.ORCID 0000-0003-3082-6789
Hongyi YanDepartment of Neurology, Beijing Tiantan Hospital Capital Medical University Beijing China.ORCID 0000-0001-5190-6345
Xia MengDepartment of Neurology, Beijing Tiantan Hospital Capital Medical University Beijing China.
Jinxi LinDepartment of Neurology, Beijing Tiantan Hospital Capital Medical University Beijing China.ORCID 0009-0005-0995-0541
Mengxing WangDepartment of Neurology, Beijing Tiantan Hospital Capital Medical University Beijing China.
Hao LiDepartment of Neurology, Beijing Tiantan Hospital Capital Medical University Beijing China.
Qin XuDepartment of Neurology, Beijing Tiantan Hospital Capital Medical University Beijing China.ORCID 0000-0002-8039-709X
Pan ChenDepartment of Neurology, Beijing Tiantan Hospital Capital Medical University Beijing China.
Anxin WangDepartment of Neurology, Beijing Tiantan Hospital Capital Medical University Beijing China.ORCID 0000-0003-4351-2877
Yilun ZhouDepartment of Nephrology Beijing Tiantan Hospital, Capital Medical University Beijing China.ORCID 0000-0002-3651-7509
Yongjun WangDepartment of Neurology, Beijing Tiantan Hospital Capital Medical University Beijing China.ORCID 0000-0002-9976-2341

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe impact of long-term renal function change on stroke outcomes remains unclear. This study used the CNSR-III (Third China National Stroke Registry) cohort to determine whether changes in estimated glomerular filtration rate based on creatinine and cystatin C (eGFR METHODS AND

resultsWe included 4270 patients with centrally tested serum creatinine and cystatin C at admission and 1 year post admission and evaluated 5-year follow-up data. Patients were stratified into quintiles based on the 1-year changes in eGFR. The primary outcomes included all-cause mortality, stroke disability, and stroke recurrence. In patients with acute ischemic stroke, the mean baseline eGFR

conclusionsBoth the decline and increase in eGFR

Indexed as

CreatinineCystatin CGlomerular Filtration RateIschemic StrokeKidneyStrokeAgedBiomarkersChinaFemaleFollow-Up StudiesHumansMaleMiddle AgedPrognosisRecurrenceBiomarkersCreatinineCST3 protein, humanCystatin Cacute ischemic stroke outcomecreatininecystatin CeGFR change

Identifiers

PMID39817528
PMCPMC12054465

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.