Evidence map›Paper›PMID 39817250›Full record

ArticleAnnals of translational medicine2024

Nationwide trends and outcomes of percutaneous coronary intervention for stable ischemic heart disease in end-stage kidney disease: a longitudinal study.

Rhythm Vasudeva, Harsh Mehta, Wan-Chi Chan, Sania Jiwani, Sri G Yarlagadda, Prakash Acharya, Prasad Gunasekaran, Georges Hajj, Mark Wiley, Eric Hockstad and 2 more

Abstract read
In one paragraph

Article in Annals of translational medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rhythm VasudevaDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Harsh MehtaDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Wan-Chi ChanDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Sania JiwaniDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Sri G YarlagaddaDivision of Nephrology and Hypertension, Department of Internal Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Prakash AcharyaDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Prasad GunasekaranDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Georges HajjDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Mark WileyDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Eric HockstadDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Peter TadrosDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.
Kamal GuptaDepartment of Cardiovascular Medicine, University of Kansas Medical Center, Kansas City, KS, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Patients with end-stage kidney disease (ESKD) are at high risk for coronary artery disease. We investigate the trends and outcomes of percutaneous coronary intervention (PCI) for stable ischemic heart disease (SIHD) in patients with ESKD. Methods: We utilized the United States Renal Data System [2010-2018] to include adult patients with ESKD on dialysis for at least 3 months who underwent PCI for SIHD. Patients with myocardial infarction during index hospitalization, history of coronary artery bypass graft or renal transplantation and without Medicare AB coverage were excluded. Trends and related outcomes, including mortality and revascularization rate, were studied. Results: The mean age was 65.1 years with 57.5% male and a majority White (64.5%). The dialysis duration was ≤5 years in 83.3% patients. Hypertension (97.6%) and diabetes mellitus (76.8%) were the most common comorbidities. PCI procedures per 1,000 ESKD patients dropped from 6.2 in 2010 to 2.6 in 2018 (P<0.001) while the index hospitalization mortality increased from 0.9% to 3.0% (P<0.001). The 30-day and 1-year mortality also significantly increased from 3.2% to 6.1% and 26.5% to 31.9%, respectively. However, 1-year repeat revascularization rates dropped from 19.8% to 17.0% between 2010-2018 (P<0.001). A significant increase in comorbidity burden was also noted. Conclusions: We demonstrate a consistent decrease in PCI rates for SIHD in ESKD patients. However, the in-hospital mortality has increased significantly, in part, due to an increasing high-risk profile of these patients. Our results call for individualized clinical decision-making when exploring revascularization options in ESRD patients with SIHD.

Indexed as

coronaryoutcomesRenal diseaserevascularizationtrend

Identifiers

PMID39817250
PMCPMC11729801

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.