ArticleJACC. Advances2024
Associations With Adverse Postoperative Outcomes in Children Undergoing Atrial Septal Defect Closure in Lower-Resource Settings.
Article in JACC. Advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
3 citing papers in PubMed.
- Review
- Atrial Septal Defects: From Embryology to Pediatric Pulmonary Hypertension.Journal of clinical medicine · 2025Review
- Congenital Heart Disease Surgery in Low-Resource Settings: Quality Improvement Is Key.JACC. Advances · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Atrial septal defects (ASDs) are a common cause of congenital heart disease worldwide. Objectives: The purpose of the study was to assess change over time in surgical outcomes for ASD repair and identify patient-level risk factors for adverse postoperative outcomes. Methods: We analyzed cases of isolated ASD in patients <18 years from 2010 to 2020 from 71 sites participating in the International Quality Improvement Collaborative for Congenital Heart Disease. Regression models identified associations between patient characteristics and 3 outcome variables: in-hospital death, major infection, and intensive care unit (ICU) length of stay (LOS). Results: Among 9,127 ASD closures, 7,653 (84%) were ASD secundum. A total of 914 patients (10%) had ASD repair at <1 year. A total of 3,363 (38%) were <5% for World Health Organization weight/body mass index for age percentile. A total of 2,511 surgeries (28%) occurred from 2010 to 2014 and 6,616 (72%) from 2015 to 2020. Overall, in-hospital mortality was 0.45% and major infection was 0.65%. Median ICU LOS was 27 hours. Prematurity (odds ratio [OR]: 9.62; Conclusions: High-quality surgical programs in low- and middle-income countries experienced an over 5-fold reduction in in-hospital mortality and an over 2-fold reduction of infection after ASD surgery over the past decade, with rates now comparable to some high-income settings, supporting equitable access to life-saving surgery.
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