Evidence map›Paper›PMID 39817034›Full record

ArticleOpen forum infectious diseases2025

Preference for HIV Pre-exposure Prophylaxis Access Among Men who Have Sex With Men in China: A Discrete Choice Experiment.

Wenting Huang, Daniel Stegmueller, Jessica M Sales, Guodong Mi, Fei Yu, Yufen Liu, Patrick S Sullivan, Aaron J Siegler, Jason J Ong

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Wenting HuangDepartment of Behavioral, Social, and Health Education Sciences, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0003-0032-6986
Daniel StegmuellerDepartment of Political Science, Duke University, Durham, North Carolina, USA.ORCID https://orcid.org/0000-0003-3188-1253
Jessica M SalesDepartment of Behavioral, Social, and Health Education Sciences, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-1571-8192
Guodong MiDanlan Public Welfare, Beijing, China.ORCID https://orcid.org/0000-0002-0401-7753
Fei YuDanlan Public Welfare, Beijing, China.
Yufen LiuNational Center for AIDS/STD Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Patrick S SullivanDepartment of Epidemiology, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0002-7728-0587
Aaron J SieglerDepartment of Behavioral, Social, and Health Education Sciences, Emory University, Atlanta, Georgia, USA.ORCID https://orcid.org/0000-0001-5553-7540
Jason J OngMelbourne Sexual Health Centre, Alfred Health, Melbourne, Australia.ORCID https://orcid.org/0000-0001-5784-7403

Funding

Virology and Molecular Biomarkers CoreP30AI050409 · NIAID · EMORY UNIVERSITY · PI Ann M Chahroudi, Colleen F Kelley · 2002 to 2026
$74.0M
Population-based survey of SARS-CoV-2 infection and immune responseR01AI143875 · NIAID · EMORY UNIVERSITY · PI SIEGLER, AARON JULIUS, SULLIVAN, PATRICK SEAN · 2019 to 2023
$9.2M
NIAID NIH HHS P30 AI050409NIAID NIH HHS R01 AI143875
6 · The paper itself

Abstract

Background: HIV pre-exposure prophylaxis (PrEP) is highly effective but not widely used by men who have sex with men (MSM; 27%) in China. Methods: In June 2023, an online cross-sectional survey with a discrete choice experiment (DCE) was distributed to PrEP-eligible MSM in China who were at least 18 years old. The DCE explored attributes of PrEP modality (daily pill, on-demand pill, injections, implants), clinical care model (same-day, 2-visit, telehealth prescription), medication pickup (clinic, community health center, pharmacy, MSM-focused community-based organization, home delivery), enhanced support (self-management, smartphone app, text reminder, anonymous peer support group), and cost. Results: A total of 1013 MSM completed the survey; the average age was 31 years, and a quarter had used PrEP. The most influential attributes were cost (relative importance: 64.6%), followed by PrEP modality (27.7%), medication pickup (4.0%), enhanced support (3.5%), and clinical care model (0.2%). The most preferred ways to access PrEP were no-cost on-demand pill, medication home delivery, self-management, and telehealth. The predicted uptake of on-demand PrEP was higher than other modalities, increasing from 22% with no subsidy to 79% with full subsidy, holding the other 3 attributes constant. Conclusions: Chinese MSM have strong preferences regarding accessing PrEP: Low cost is a critical priority, especially important because medication and clinical care are currently entirely unsubsidized in China. Preferences for on-demand PrEP and home delivery indicate methods that the health care system can utilize to best meet the needs of MSM and factors that should be incorporated into future interventions.

Indexed as

ChinaHIV preventionmen who have sex with menpre-exposure prophylaxispreference

Identifiers

PMID39817034
PMCPMC11733822

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.