Evidence map›Paper›PMID 39817011›Full record

ArticleJournal of arrhythmia2025

Sex differences in atrial fibrillation in India: Insights from the Kerala-AF registry.

Peter Calvert, Yang Chen, Ying Gue, Dhiraj Gupta, Jinbert Lordson Azariah, A George Koshy, Geevar Zachariah, K U Natarajan, Gregory Y H Lip, Bahuleyan Charantharayil Gopalan and 1 more

Abstract read
In one paragraph

Article in Journal of arrhythmia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Observational
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peter CalvertLiverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University, and Liverpool Heart and Chest Hospital Liverpool UK.ORCID https://orcid.org/0000-0002-8401-4033
Yang ChenLiverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University, and Liverpool Heart and Chest Hospital Liverpool UK.
Ying GueLiverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University, and Liverpool Heart and Chest Hospital Liverpool UK.
Dhiraj GuptaLiverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University, and Liverpool Heart and Chest Hospital Liverpool UK.ORCID https://orcid.org/0000-0002-3490-090X
Jinbert Lordson AzariahDepartment of Clinical Research Ananthapuri Hospitals and Research Institute Thiruvananthapuram India.
A George KoshyCosmopolitan Hospital Trivandrum Kerala India.
Geevar ZachariahMother Hospital Thrissur Kerala India.
K U NatarajanAmrita Institute of Medical Sciences Kochi Kerala India.
Gregory Y H LipLiverpool Centre for Cardiovascular Science at University of Liverpool, Liverpool John Moores University, and Liverpool Heart and Chest Hospital Liverpool UK.ORCID https://orcid.org/0000-0002-7566-1626
Bahuleyan Charantharayil GopalanDepartment of Cardiology Ananthapuri Hospitals and Research Institute Thiruvananthapuram India.
Kerala AF Registry Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Much data informing sex differences in atrial fibrillation (AF) comes from Western cohorts. In this analysis, we describe sex differences in Kerala, India, using the Kerala-AF registry-the largest AF registry from the Indian subcontinent. Methods: Patients aged ≥18 years were recruited from 53 hospitals across Kerala. Patients were compared for demographics, treatments, and 12-month outcomes, including major adverse cardiovascular events (MACE) and bleeding. Results: Male patients were more likely to have a smoking and/or alcohol history and had more ischaemic heart disease (46.2% vs. 25.5%; Conclusion: In this large AF cohort from India, male patients had a higher prevalence of ischaemic heart disease, smoking, and alcohol use, while female patients had a higher prevalence of valvular heart disease. MACE did not differ by sex, though bleeding was more common in males. Almost a quarter of patients were not anticoagulated despite raised thromboembolic risk.

Indexed as

atrial fibrillationIndiaKeralasex differencesSouth Asia

Identifiers

PMID39817011
PMCPMC11730713

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.