Evidence map›Paper›PMID 39816881›Full record

ReviewFrontiers in child and adolescent psychiatry2023

Observing the behavioural effects of methylphenidate in children and adolescents with ASD-ADHD dual diagnosis: A mini review.

Danilo Dimitri, Giuliana Delia, Maurizio Arduino, Nazarena Turco, Franco Fioretto

Abstract readReview
In one paragraph

Review in Frontiers in child and adolescent psychiatry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Danilo DimitriDepartment of Psychology, University of Turin, Turin, Italy.
Giuliana DeliaDepartment of Child Neuropsychiatry, A.S.L. CN1- Mondovì, Neuropsichiatria Infantile, Mondovì, Italy.
Maurizio ArduinoCenter for Autism and Asperger's Syndrome, A.S.L. CN1, Mondovì, Italy.
Nazarena TurcoCenter for Autism and Asperger's Syndrome, A.S.L. CN1, Mondovì, Italy.
Franco FiorettoDepartment of Child Neuropsychiatry, A.S.L. CN1- Mondovì, Neuropsichiatria Infantile, Mondovì, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research aim: The aim of this study is to focus on the main neurophysiological aspects of attention-deficit/hyperactivity disorder (ADHD) and autism spectrum disorder (ASD) and the current pharmacological treatment used for the management of hyperactivity and attention deficits in children aged 6-20 years with a diagnosis of ASD, not associated with other genetic or epileptic disorders, such as Fragile X Syndrome (FXS), Tuberous Sclerosis, Kleefstra Syndrome or Angelman Syndrome. Methods: This mini review was conducted according to the Conclusions: Three main aspects emerged from the review: (1) According to the existing literature, new randomized controlled trials are needed to ensure a better understanding of the most effective drug treatments for dual-diagnosed ASD-ADHD patients and of the related behavioural effects. Currently, the use of drugs varies depending on psychiatric comorbidity, symptoms, age and gender and there is no univocal reference therapy; (2) Methylphenidate (MPH) has currently been shown to be the most suitable drug for the treatment of hyperactivity and inattention in individuals diagnosed with ASD and ADHD; (3) There is a need to create and evaluate appropriate tests to analyse more specific patterns of behaviour presented in the two conditions.

Indexed as

ADHDASDASD-ADHDattention deficit hyperactivity disorderautism spectrum disorderchildren and adolescentscomorbiditymethylphenidate

Identifiers

PMID39816881
PMCPMC11732115

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.