Evidence map›Paper›PMID 39816635›Full record

ArticleVeterinary research forum : an international quarterly journal2024

Utilization of mannan oligosaccharides as antibiotic substitutes in laying hens.

Rosa Angélica Sanmiguel Plazas, Olga Teresa Barreto-Cruz, Juan Antonio Javierre, Diana Camila Mogollon Vergara, María Leandra León Miranda, Moris Andrés Sosa Vargas, Erica Liseth Carvajal

Abstract read
In one paragraph

Article in Veterinary research forum : an international quarterly journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. AOpen veterinary journal · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Rosa Angélica Sanmiguel PlazasDepartment of Animal Production, Faculty of Veterinary Medicine and Animal Science, Universidad Cooperativa de Colombia, Ibague, Colombia.
Olga Teresa Barreto-CruzDepartment of Animal Production, Faculty of Veterinary Medicine and Animal Science, Universidad Cooperativa de Colombia, Ibague, Colombia.
Juan Antonio JavierreDepartment of Research (Innovation and Development), Tekzol SAS, Bogota, Colombia.
Diana Camila Mogollon VergaraDepartment of Animal Production, Faculty of Veterinary Medicine and Animal Science, Universidad Cooperativa de Colombia, Ibague, Colombia.
María Leandra León MirandaDepartment of Animal Production, Faculty of Veterinary Medicine and Animal Science, Universidad Cooperativa de Colombia, Ibague, Colombia.
Moris Andrés Sosa VargasDepartment of Animal Production, Faculty of Veterinary Medicine and Animal Science, Universidad Cooperativa de Colombia, Ibague, Colombia.
Erica Liseth CarvajalDepartment of Animal Production, Faculty of Veterinary Medicine and Animal Science, Universidad Cooperativa de Colombia, Ibague, Colombia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Among global concerns about antibiotic resistance, it is necessary to identify food-safe alternatives to enhance production. This study aimed to evaluate the impact of mannan oligosaccharides (MOS) inclusion to replace antibiotic growth promoters (AGP) in the diets of ISA Brown laying hens aged between 23 and 31 weeks. Two hundred forty hens were grouped into five treatments: Control, AGP (130 ppm of enramycin 8.00%), and 100, 200, and 400 ppm of MOS. Each treatment had 16 experimental units (each unit with n = 3) in a randomized block experimental design. Productive data (egg production %, feed intake, egg weight), egg quality variables (albumin height, yolk weight, albumin, yolk %, weight eggshell, eggshell %, equator thickness, width-pole thickness, and Haugh units), organ weights (ovary, liver, and cecum) and jejunal histomorphometry were analyzed. The egg production was not affected by the substitution of AGP by MOS. Furthermore, MOS supplementation resulted in significantly increased feed intake, larger egg weight, higher yolk weight and higher body and ovarium weight compared to the AGP group. Besides, MOS supplementation at 400 ppm demonstrated significant improvements in jejunal villus morphology indicating enhanced intestinal health. These findings highlighted the potential of MOS as an alternative to AGP, offering benefits such as improved feed intake, egg quality and intestinal health in laying hens at 400 ppm.

Indexed as

Egg qualityIntestinal healthPerformancePrebioticsResistance

Identifiers

PMID39816635
PMCPMC11729109

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.