Evidence map›Paper›PMID 39816316›Full record

ArticleCureus2024

Clinical Case Scenarios in the Management of Non-diabetic Chronic Kidney Diseases.

Sharad Sheth

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Sharad ShethNephrology, Kokilaben Dhirubhai Ambani Hospital and Medical Research Institute, Mumbai, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Research conducted in India has shown that there is a high prevalence of non-diabetic kidney disease (NDKD) among Indian patients. Sodium-glucose co-transporter 2 inhibitors (SGLT2i) are emerging as potential treatments for preventing the progression of chronic kidney disease to advanced stages, regardless of their anti-diabetic effects. Dapagliflozin, which has been approved by the Central Drugs Standard Control Organization, is the SGLT2i drug class approved for use in both DKD and NDKD patients. Taking this validation into account, the case series was planned to showcase four different real-life case studies in an Indian clinical setting, which involved the utilization of dapagliflozin in different patient profiles with NDKD. The real-world cases substantiate the renoprotective effects of dapagliflozin as seen by changes in the estimated glomerular filtration rate levels and proteinuria post-treatment. These case scenarios highlight the benefits of reducing renal risk factors in patients with NDKD. Notably, in all the cases, the risk of renal disease progression was delayed in NDKD patients with dapagliflozin.

Indexed as

dapagliflozinndkdnon-diabetic kidney diseaseproteinuriarenoprotectivesglt2isodium-glucose co-transporter 2 inhibitor

Identifiers

PMID39816316
PMCPMC11733397

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.