Evidence map›Paper›PMID 39816308›Full record

ArticleCureus2024

The Importance of Clinical History in the Etiological Diagnosis of Diffuse Alveolar Hemorrhage Associated With Improper Adrenaline Use.

João Nuno Patrício, Ana Rafael, Filipe Conceição, José Manuel Pereira, José-Artur Paiva

Abstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

João Nuno PatrícioDepartment of Intensive Care Medicine, Hospital Beatriz Ângelo, Loures, PRT.
Ana RafaelDepartment of Intensive Care Medicine, Centro Hospitalar De Trás-Os-Montes E Alto Douro, Vila Real, PRT.
Filipe ConceiçãoDepartment of Intensive Care Medicine, Centro Hospitalar Universitário de São João, Porto, PRT.
José Manuel PereiraDepartment of Intensive Care Medicine, Centro Hospitalar Universitário de São João, Porto, PRT.
José-Artur PaivaDepartment of Intensive Care Medicine, Centro Hospitalar Universitário de São João, Porto, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This case involves a 21-year-old male healthcare student with a medical history of HIV-1 infection for two years and anxiety disorder. He presented to the emergency department with hemoptysis and dyspnea of sudden onset. A thoracic CT scan revealed multiple bilateral nodular ground-glass opacities suggestive of diffuse alveolar hemorrhage (DAH). Due to hypoxemic respiratory failure, noninvasive ventilatory support was initiated. A bronchoalveolar lavage confirmed the presence of blood. He also showed an elevated troponin I, peaking at 2,915 ng/mL, with no electrocardiographic or echocardiographic abnormalities. Assuming an immune etiology, high-dose corticosteroids were initiated, with three days of methylprednisolone 1 g. However, the entire etiological study for DAH turned out negative. During a follow-up clinical interview, the patient admitted to having self-administered 1 mg of intravenous adrenaline shortly before the onset of symptoms. The patient showed a favorable evolution, with no recurrence of symptoms, allowing for oxygen therapy weaning. A follow-up chest CT on the ninth day of hospitalization showed no significant alterations. This case highlights the importance of a thorough history in determining the etiology of a potentially fatal disease, adding intravenous epinephrine as a potential trigger of hemoptysis due to exogenous agents.

Indexed as

adrenalinedyspneahemoptysispulmonary alveolar hemorrhagerespiratory failure

Identifiers

PMID39816308
PMCPMC11732640

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.