ArticleCureus2024
The Importance of Clinical History in the Etiological Diagnosis of Diffuse Alveolar Hemorrhage Associated With Improper Adrenaline Use.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
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Abstract
This case involves a 21-year-old male healthcare student with a medical history of HIV-1 infection for two years and anxiety disorder. He presented to the emergency department with hemoptysis and dyspnea of sudden onset. A thoracic CT scan revealed multiple bilateral nodular ground-glass opacities suggestive of diffuse alveolar hemorrhage (DAH). Due to hypoxemic respiratory failure, noninvasive ventilatory support was initiated. A bronchoalveolar lavage confirmed the presence of blood. He also showed an elevated troponin I, peaking at 2,915 ng/mL, with no electrocardiographic or echocardiographic abnormalities. Assuming an immune etiology, high-dose corticosteroids were initiated, with three days of methylprednisolone 1 g. However, the entire etiological study for DAH turned out negative. During a follow-up clinical interview, the patient admitted to having self-administered 1 mg of intravenous adrenaline shortly before the onset of symptoms. The patient showed a favorable evolution, with no recurrence of symptoms, allowing for oxygen therapy weaning. A follow-up chest CT on the ninth day of hospitalization showed no significant alterations. This case highlights the importance of a thorough history in determining the etiology of a potentially fatal disease, adding intravenous epinephrine as a potential trigger of hemoptysis due to exogenous agents.
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