Evidence map›Paper›PMID 39816306›Full record

ArticleCureus2024

Molecular Detection of Tick-Borne Bacterial Pathogens in Patients With Undifferentiated Febrile Illness in India Using a Flow Chip Assay.

Chandan K Thakur, E V Vinayaraj, Rama Chaudhry

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chandan K ThakurDepartment of Clinical Microbiology, Karnali Academy of Health Sciences, Jumla, NPL.
E V VinayarajDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, New Delhi, IND.
Rama ChaudhryDepartment of Microbiology, All India Institute of Medical Sciences, New Delhi, New Delhi, IND.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTick-borne diseases (TBDs) play a crucial role in human morbidity and mortality, as ticks are highly effective in spreading diseases by transmitting harmful pathogens to humans and animals. The last few decades have seen an increase in the number of recognized tick-borne pathogens and the incidence of TBD worldwide. Several of these diseases are ubiquitous in India. However, in India, there is limited information on the molecular detection of tick-borne pathogens in patients with undifferentiated febrile illness. The study aims to investigate tick-borne pathogens among undifferentiated febrile patients in India using a multiplex polymerase chain reaction (PCR)-based assay.

methodsA total of 120 blood samples were collected from patients with undifferentiated febrile illnesses of all ages. The samples were tested for a panel of (seven) tick-borne pathogens (

resultsAmong the 120 samples tested, one was positive for spotted fever

conclusionOur knowledge of TBD is steadily advancing with the discovery of novel pathogens and the development of cutting-edge diagnostic tools. Although traditional diagnostic methods like serology and microscopy will remain essential for the diagnosis of TBD, the implementation of advanced molecular diagnostics such as TBFC will enhance our understanding of these diseases by enabling the identification of emerging pathogens and offering more precise and timely diagnoses.

Indexed as

febrile illnesshybrispotrickettsiatick-borne bacterial flow chiptick-borne diseasevectorzoonosis

Identifiers

PMID39816306
PMCPMC11733704

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.