Evidence map›Paper›PMID 39816274›Full record

ArticleCureus2024

Models and Biomarkers for Local Response Prediction in Early-Stage and Oligometastatic Non-small Cell Lung Cancer Patients Treated With Stereotactic Body Radiation Therapy Using Machine Learning.

Gemini Ramasamy, Thierry Muanza, Goulnar Kasymjanova, Jason Agulnik

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Gemini RamasamyDepartment of Experimental Medicine, McGill University, Montreal, CAN.
Thierry MuanzaDivision of Radiation Oncology, Sir Mortimer B. Davis Jewish General Hospital, McGill University, Montreal, CAN.
Goulnar KasymjanovaDepartment of Medicine and Pulmonary Oncology, Sir Mortimer B. Davis Jewish General Hospital, McGill University, Montreal, CAN.
Jason AgulnikAnna and Peter Brojde Lung Cancer Center, Sir Mortimer B. Davis Jewish General Hospital, McGill University, Montreal, CAN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background A minority of patients receiving stereotactic body radiation therapy (SBRT) for non-small cell lung cancer (NSCLC) are not good responders. Radiomic features can be used to generate predictive algorithms and biomarkers that can determine treatment outcomes and stratify patients to their therapeutic options. This study investigated and attempted to validate the radiomic and clinical features obtained from early-stage and oligometastatic NSCLC patients who underwent SBRT, to predict local response. Methodology A single-institution, Institutional Review Board (IRB)-approved retrospective review was conducted on adult patients with early-stage and oligometastatic SBRT-treated NSCLC at the Jewish General Hospital. The study included 98 patients (82 with early-stage NSCLC and 16 with oligometastatic disease), with a median age of 76 years and a male-to-female ratio of 46:52. A total of 116 lesions were treated with SBRT between 2009 and 2022. Radiomics features (

Indexed as

local responsenon-small cell lung cancerpredictiveradiomicsstereotactic body radiation therapy

Identifiers

PMID39816274
PMCPMC11734944

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.