Evidence map›Paper›PMID 39816157›Full record

ArticleBiomedical optics express2025

Out-of-focus signal rejection for

Qi Pian, Baoqiang Li, Ikbal Şencan-Eğilmez, Xiaojun Cheng, Jay Dubb, Xinyue Huang, Buyin Fu, Srinivasa Rao Allu, Mohammad Abbas Yaseen, Anna Devor and 2 more

Abstract read
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Out-of-focus signal rejection forBiomedical optics express · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Qi PianAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.ORCID https://orcid.org/0000-0003-4760-8446
Baoqiang LiAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Ikbal Şencan-EğilmezAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Xiaojun ChengNeurophotonics Center, Department of Biomedical Engineering, Boston University, Boston, MA 02215, USA.
Jay DubbAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Xinyue HuangAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Buyin FuAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Srinivasa Rao AlluDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Mohammad Abbas YaseenAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Anna DevorAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.
Sergei A VinogradovDepartment of Biochemistry and Biophysics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Sava SakadžićAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown, MA 02129, USA.

Funding

Project 4U19NS123717 · NINDS · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI MISHNE, GAL · 2021 to 2025
$13.4M
Investigating the Microvascular Mechanisms of O2 Supply-Demand Mismatch in Small Vessel Disease using Novel High-Resolution Optical ImagingR01NS115401 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI AYATA, CENK, SAKADZIC, SAVA · 2020 to 2024
$3.5M
The effect of circadian rhythm disruptions on the angiogenic response to hypoperfusion in the AD brainR01AG081841 · NIA · MASSACHUSETTS GENERAL HOSPITAL · PI Ken Arai, Eng H. Lo · 2023 to 2026
$3.0M
Two-Photon Microscopy of Oxygen Consumption in the BrainR01NS091230 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI SAKADZIC, SAVA · 2015 to 2019
$2.4M
Multiscale modeling of cerebral blood flow and oxygen transportU01HL133362 · NHLBI · UNIVERSITY OF ARIZONA · PI SECOMB, TIMOTHY W. · 2017 to 2021
$2.0M
Effects of intrinsic and drug-induced neuromodulation on functional brain imagingR01DA050159 · NIDA · BOSTON UNIVERSITY (CHARLES RIVER CAMPUS) · PI DEVOR, ANNA · 2020 to 2024
$1.9M
Two-photon Imaging of Oxygen and Blood Flow in Retinal and Cerebral VasculatureRF1NS121095 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI SAKADZIC, SAVA, SHAHIDI, MAHNAZ · 2021 to 2021
$1.9M
Oxygen imaging by phosphorescence quenchingU24EB028941 · NIBIB · UNIVERSITY OF PENNSYLVANIA · PI VINOGRADOV, SERGEI · 2019 to 2023
$1.6M
Two-photon Imaging of Oxygen and Blood Flow in Retinal and Cerebral VasculatureR01NS121095 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Sava Sakadzic, Mahnaz Shahidi · 2024 to 2026
$1.3M
Effects of standard fMRI calibrations on the diverse microvascular blood flow and oxygenation responses in cortical layersR00MH120053 · NIMH · WASHINGTON UNIVERSITY · PI SENCAN-EGILMEZ, IKBAL · 2022 to 2024
$698k
NHLBI NIH HHS U01 HL133362NIA NIH HHS R01 AG081841NIBIB NIH HHS U24 EB028941NIDA NIH HHS R01 DA050159NIMH NIH HHS R00 MH120053NINDS NIH HHS R01 NS091230NINDS NIH HHS R01 NS115401NINDS NIH HHS R01 NS121095NINDS NIH HHS RF1 NS121095NINDS NIH HHS U19 NS123717
6 · The paper itself

Abstract

Two-photon phosphorescence lifetime microscopy has been a key tool for studying cerebral oxygenation in mice. However, the accuracy of the partial pressure of oxygen (pO

Identifiers

PMID39816157
PMCPMC11729295

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.