ArticleBiomedical optics express2025
Optical diffraction tomography using a self-reference module.
Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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Who cites it
3 citing papers in PubMed.
- Electrically Switchable Diffraction Grating Based on Electrophoretic Redistribution of Carbon Black Nanoparticles.Small (Weinheim an der Bergstrasse, Germany) · 2026Article
- Optical diffraction tomographic microscopy: a cutting-edge label-free three-dimensional bioimaging.Biophysics reports · 2026Article
- Recent breakthroughs in digital holography, 2D/3D imaging, and holographic optical elements: introduction.Biomedical optics express · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Optical diffraction tomography enables label-free, 3D refractive index (RI) imaging of biological samples. We present a novel, cost-effective approach to ODT that employs a modular design incorporating a self-reference holographic capture module. This two-part system consists of an illumination module and a capture module that can be seamlessly integrated with any life-science microscope using an automated alignment protocol. The illumination module employs a galvo-scanner system, providing precise control over the angular illumination, while the capture module utilises the principle of self-reference off-axis holography. The design has a compact form factor, simple alignment, and reduced cost. Furthermore, our system offers the capability to switch between two imaging modalities, ODT and real-time synthetic aperture digital holographic microscopy (SA-DHM), a unique feature not found in other setups. Experimental results are provided using a kidney cancer cell line. Experimental results are provided using a kidney cancer cell line.
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Registered trials
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