Evidence map›Paper›PMID 39816152›Full record

ArticleBiomedical optics express2025

MXene-based SERS spectroscopic analysis of exosomes for lung cancer differential diagnosis with deep learning.

Xi Chen, Hongyi Liu, Dandan Fan, Nan Chen, Pei Ma, Xuedian Zhang, Hui Chen

Abstract read
In one paragraph

Article in Biomedical optics express, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xi ChenKey Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, 200093 Shanghai, China.
Hongyi LiuKey Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, 200093 Shanghai, China.
Dandan FanKey Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, 200093 Shanghai, China.
Nan ChenSchool of Electrical Engineering and Automation, Nantong University, Nantong 226019, China.ORCID https://orcid.org/0000-0002-2077-3284
Pei MaKey Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, 200093 Shanghai, China.ORCID https://orcid.org/0000-0001-8485-6065
Xuedian ZhangKey Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, 200093 Shanghai, China.
Hui ChenKey Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, 200093 Shanghai, China.ORCID https://orcid.org/0000-0002-4391-9717

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lung cancer with heterogeneity has a high mortality rate due to its late-stage detection and chemotherapy resistance. Liquid biopsy that discriminates tumor-related biomarkers in body fluids has emerged as an attractive technique for early-stage and accurate diagnosis. Exosomes, carrying membrane and cytosolic information from original tumor cells, impart themselves endogeneity and heterogeneity, which offer extensive and unique advantages in the field of liquid biopsy for cancer differential diagnosis. Herein, we demonstrate a Gramian angular summation field and MobileNet V2 (GASF-MobileNet)-assisted surface-enhanced Raman spectroscopy (SERS) technique for analyzing exosomes, aimed at precise diagnosis of lung cancer. Specifically, a composite substrate was synthesized for SERS detection of exosomes based on Ti

Identifiers

PMID39816152
PMCPMC11729284

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.