Evidence map›Paper›PMID 39816071›Full record

ArticleNarra J2024

Association between vitamin D levels with IL-6 and IL-10 in umbilical cord blood of infants.

Muhammad N Massi, Bahrul Fikri, Azwin M Putera, Sofa D Alfian, Nadirah R Ridha, Sri H Putri, Ummi Chaera, Israini W Iskandar, Naoki Shimojo

Abstract read
In one paragraph

Article in Narra J, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Muhammad N MassiDepartment of Microbiology, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.
Bahrul FikriDepartment of Pediatrics, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.
Azwin M PuteraDepartment of Child Health, Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia.
Sofa D AlfianDepartment of Pharmacology and Clinical Pharmacy, Universitas Padjadjaran, Sumedang, Indonesia.
Nadirah R RidhaDepartment of Child Health, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.
Sri H PutriDivision of Pediatric Hematology-Oncology, Department of Child Health, Faculty of Medicine, Universitas Hasanuddin, Makassar, Indonesia.
Ummi ChaeraBiomedical Science Master Program, Post Graduate School, Universitas Hasanuddin, Makassar, Indonesia.
Israini W IskandarBiomedical Science Master Program, Post Graduate School, Universitas Hasanuddin, Makassar, Indonesia.
Naoki ShimojoCenter for Preventive Medical Sciences, Chiba University, Chiba, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A worldwide issue, vitamin D deficiency affects pregnant mothers and babies everywhere, including Indonesia. It involves the adaptive immune system by controlling the production of pro-and anti-inflammatory cytokines and the balance between humoral (Th2) and cell-mediated (Th1) immunity. The aim of this study was to investigate the relationship between vitamin D and the cytokines IL-6 and IL-10 in infants. It also examined the relationship between ferritin and IL-6/IL-10 in newborns. The study collected 114 umbilical cord blood samples from term-born mothers without clinical symptoms. IL-6 and IL-10 were among the cytokine profiles measured by the enzyme-linked immunosorbent assay (ELISA). SPSS was used for statistical analysis, and an in -silico investigation was carried out to examine the molecular relationships between vitamin D and IL-6/IL-10. Using the 20 ng/mL as the cut-off for vitamin D insufficiency suggested the insignificant association of vitamin D with IL-6 (

Indexed as

Fetal BloodInterleukin-10Interleukin-6Vitamin DVitamin D DeficiencyAdultFemaleHumansIndonesiaInfant, NewbornMalePregnancyIL10 protein, humanIL6 protein, humanInterleukin-10Interleukin-6Vitamin DFerritinIL-10IL-6umbilical cordvitamin D

Identifiers

PMID39816071
PMCPMC11731675

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.