ArticleKidney research and clinical practice2025
The impact of body mass index on mortality according to age in hemodialysis patients: an analysis of the Korean Renal Data System.
Article in Kidney research and clinical practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed.
- Associations Between Body Mass Index and Clinical Outcomes Stratified by Age in Patients Undergoing Maintenance Hemodialysis.Hemodialysis international. International Symposium on Home Hemodialysis · 2026Article
- Development and validation of an inflammatory index-based interpretable machine learning model for mortality risk stratification in hemodialysis patients.European journal of medical research · 2026Article
- Individualizing Kt by sex and body surface area: implications for survival in hemodialysis patients.Clinical kidney journal · 2026Article
- Impact of Annual Dry Weight Changes on Mortality and Cardiovascular Outcomes in Patients Undergoing Haemodialysis.Journal of cachexia, sarcopenia and muscle · 2025Article
- Application of Cluster Analysis Based on SHAP Values in Hemodialysis Patients Using Arteriovenous Fistula.International journal of general medicine · 2025Article
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18 authors.
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Abstract
The impact of age on the relationship between body mass index (BMI) and all-cause mortality in hemodialysis (HD) patients is not clearly understood. Using data from the Korean Renal Data System (2001-2022), we analyzed 66,129 HD patients, stratified into young (<65 years, n = 24,589), younger-old (65-74 years, n = 17,732), and older-old (≥75 years, n = 23,808) groups. Patients were categorized into BMI quartiles, and survival outcomes were evaluated using Kaplan-Meier curves and event time ratios for the relative change in the survival time. During the follow-up period, 14,360 of the patients (21.7%) died, with a median follow-up of 3.4 years. Kaplan-Meier curves revealed poorer outcomes in lower BMI quartiles across all age groups. The lowest BMI quartile was significantly associated with a shorter survival time compared to the highest BMI quartile, with a 15% reduction in the young group (p = 0.001) and a 12% reduction in the older-old group (p = 0.002). Predicted survival time increases with rising BMI in the young group, but the rate of increase slows in the younger-old group and plateaus in the older-old group after a BMI of 25 kg/m2. Lower BMI correlates with higher mortality, particularly in younger HD patients.
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