Evidence map›Paper›PMID 39815762›Full record

ArticleGlobal spine journal2025

Malnutrition in Spine Oncology: Where Are We and What Are We Measuring?

Rafael De la Garza Ramos, Raphaële Charest-Morin, C Rory Goodwin, Scott L Zuckerman, Ilya Laufer, Nicolas Dea, Arjun Sahgal, Laurence D Rhines, Ziya L Gokaslan, Chetan Bettegowda and 13 more

Abstract read
In one paragraph

Article in Global spine journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Rafael De la Garza RamosDepartment of Neurological Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, New York, NY, USA.ORCID 0000-0002-5536-2514
Raphaële Charest-MorinCombined Neurosurgical and Orthopedic Spine Program, Department of Orthopedics Surgery, University of British Columbia, Vancouver, BC, Canada.ORCID 0000-0002-7689-1087
C Rory GoodwinDepartment of Neurosurgery, Spine Division, Duke University, Durham, NC, USA.ORCID 0000-0002-6540-2751
Scott L ZuckermanDepartment of Neurological Surgery, Vanderbilt University Medical Center, Nashville, TN, USA.
Ilya LauferDepartment of Neurological Surgery, New York University Grossman School of Medicine, New York, NY, USA.
Nicolas DeaCombined Neurosurgical and Orthopedic Spine Program, Department of Orthopedics Surgery, University of British Columbia, Vancouver, BC, Canada.
Arjun SahgalDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.
Laurence D RhinesDepartment of Neurosurgery, Division of Surgery, The University of Texas MD Anderson Cancer Center, University of Texas, Houston, TX, USA.
Ziya L GokaslanDepartment of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence, RI, USA.
Chetan BettegowdaDepartment of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Anne L VersteegDivision of Surgery, Department of Orthopaedics, University of Toronto, Toronto, ON, Canada.ORCID 0000-0003-3251-9694
Hanbo ChenDepartment of Radiation Oncology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-6447-653X
Netzer CordulaDepartment of Spine Surgery, University Hospital of Basel, Basel, Switzerland.
Daniel M SciubbaDepartment of Neurosurgery, Zucker School of Medicine at Hofstra, Long Island Jewish Medical Center and North Shore University Hospital, Northwell Health, Manhasset, NY, New York, USA.
John E O'TooleDepartment of Neurological Surgery, Rush University Medical Center, Chicago, IL, USA.
Michael G FehlingsDepartment of Surgery, Division of Neurosurgery and Spine Program, University Health Network, University of Toronto, Toronto, ON, Canada.ORCID 0000-0002-5722-6364
Naresh KumarDepartment of Orthopaedic Surgery, National University Health System, Singapore, Singapore.
Alexander C DischUniversity Comprehensive Spine Center, University Center for Orthopedics, Traumatology and Plastic Surgery, University Hospital Carl Gustav Carus, Technische Universität Dresden, Dresden, Germany.
Byron StephensDeparment of Orthopedic Surgery, Vanderbilt University Medical Center, Nashville, TN, United States.
Tony GoldschlagerDepartment of Neurosurgery, Monash Health, Melbourne, VIC, Australia.ORCID 0000-0001-9572-0227
Michael H WeberSpine Surgery Program, Department of Surgery, Montreal General Hospital, McGill University Health Center, Montreal, QC, Canada.
John H ShinDepartment of Neurosurgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA.
AO Spine Knowledge Forum Tumor

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designScoping review.

objectiveTo identify which markers are used as surrogates for malnutrition in metastatic spine disease and which are the most studied outcomes associated with it.

methodsA scoping review was performed by searching the PubMed/Medline, EMBASE, and Web of Science databases up to July 2022. We searched for articles exploring markers of malnutrition in spine oncology patients including but not limited to albumin, body weight, weight loss, and nutrition indices. A narrative synthesis was performed.

resultsA total of 61 articles reporting on 31,385 patients met inclusion criteria. There were 13 different surrogate markers of nutrition, with the most common being albumin in 67% of studies (n = 41), body weight/BMI in 34% (n = 21), and muscle mass in 28% (n = 17). The most common studied outcomes were survival in 82% (n = 50), complications in 28% (n = 17), and length of stay in 10% (n = 6) of studies. Quality of life and functional outcomes were assessed in 2% (n = 1) and 3% (n = 2) of studies, respectively. Out of 61 studies, 18% (n = 11) found no association between the examined markers and outcome.

conclusionAssessment of nutritional status in patients with spinal metastases is fundamental. However, there is lack of a comprehensive and consistent way of assessing malnutrition in oncologic spine patients and therefore inconsistency in its relationship with outcomes. A consensus agreement on the assessment and definition of malnutrition in spine tumor patients is needed.

Indexed as

cancermalnutritionnutrition disorderspine oncology

Identifiers

PMID39815762
PMCPMC11988249

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.