Evidence map›Paper›PMID 39815708›Full record

ArticleEuropean journal of neurology2025

A roadmap toward promoting and improving brain health in Europe and closing the awareness and funding gap.

Paul A J M Boon, Thomas Berger, Matilde Leonardi, Tony Marson, Ulf Kallweit, Elena Moro, Antonio Toscano, Irena Rektorova, Alice Accorroni, Charlotte Scheerens and 5 more

Abstract read
In one paragraph

Article in European journal of neurology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. One brain, one mind: A joint EPA-EAN leadership perspective on brain health.European psychiatry : the journal of the Association of European Psychiatrists · 2026
    Article
  4. Natural Molecules for Brain Health and Resilience.International journal of molecular sciences · 2026
    Review
  5. Article
  6. Article
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  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Paul A J M BoonDepartment of Neurology & 4Brain, Ghent University Hospital, Ghent, Belgium.ORCID 0000-0002-4180-8896
Thomas BergerDepartment of Neurology and Comprehensive Center of Clinical Neurosciences & Mental Health, Medical University of Vienna, Vienna, Austria.
Matilde LeonardiNeurology, Public Health, Disability Unit and Coma Research Centre, Fondazione IRCCS Istituto Neurologico C. Besta, Milan, Italy.
Tony MarsonDepartment of Pharmacology and Therapeutics, University of Liverpool, Liverpool, UK.
Ulf KallweitCenter for Narcolepsy and Hypersomnias, Professorship for Narcolepsy and Hypersomnolence Research, Faculty of Health, University Witten/Herdecke, Witten, Germany.ORCID 0000-0003-1975-6919
Elena MoroGrenoble Alpes University, CHU of Grenoble, Division of Neurology, Grenoble institute of Neurosciences, Grenoble, France.
Antonio ToscanoERN-NMD Center for Neuromuscular Disorders of Messina, Department of Clinical and Experimental Medicine, University of Messina, Messina, Italy.
Irena RektorovaBrain and Mind Research, Central European Institute of Technology, Masaryk University, Brno, Czechia.ORCID 0000-0002-5455-4573
Alice AccorroniHôpitaux Universitaires de Genève, Geneva, Switzerland.
Charlotte ScheerensDepartment of Public Health and Primary Care, Ghent University, Belgium and United Nations University-CRIS, Bruges, Belgium.
Antonia BoeschEuropean Academy of Neurology, Vienna, Austria.
Michael CreanEuropean Academy of Neurology, Vienna, Austria.
Anja SanderEuropean Academy of Neurology, Vienna, Austria.
Simon LeeEuropean Academy of Neurology, Vienna, Austria.
Claudio L A BassettiDepartment of Neurology, Inselspital, University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe global burden of neurological diseases exceeds 43.1%, imposing a significant burden on patients, caregivers and society. This paper presents a roadmap to reduce this burden and improve brain health (BH) in Europe.

methodsThe roadmap is based on the European Academy of Neurology's (EAN) five-pillar BH strategy: advancing a global BH approach (P1), supporting policymaking (P2), fostering research (P3), promoting education (P4), and raising awareness of prevention and treatment (P5). It reviews current efforts, collaborations and future directions aligned with the WHO Intersectoral Global Action Plan (iGAP) for Neurological Disorders and suggests future initiatives and call for action.

resultsP1: Support WHO-iGAP through defined action points, international collaborations, in particular, the WHO BH Unit, and the EAN Brain Health Mission. P2: Collaborate with 48 national neurological societies to promote National Brain Plans (NBPs), addressing local needs, and improving access to care. P3: Advocate for more research funding; identify determinants of BH; develop preventive measures. P4: Provide educational opportunities for neurologists, public education programs, and advocacy training, including tools to educate the public. P5: Spearhead global awareness campaigns, organize public educational activities, and train BH advocates to contribute toward sustainable and long-term public health campaigns and policy engagement.

conclusionsThe paper highlights the importance of a unified approach, integrating international collaborations and local initiatives, to improve BH outcomes based on the WHO-iGAP, and support sustainable development goals, in particular SDG 3: Good Health and Well-being and SDG 4: Quality Education.

Indexed as

BrainHealth PromotionNervous System DiseasesAwarenessEuropeHumansbrainbrain healthburdenneurologystrategy

Identifiers

PMID39815708
PMCPMC11735729

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.