Evidence map›Paper›PMID 39815666›Full record

Trial reportJournal of cosmetic dermatology2025

Effectiveness of Body Remodeling and Cellulite Appearance Improvement Treatments in the Thighs Using Symmed Radiofrequency Device.

Alejandra Fernández Santos, Alejandra Iglesias Fernández, Lorena Suárez Fernández, Leticia Huergo Zapico, Susana Valero Freitag

Abstract readClinical Trial
In one paragraph

Trial report in Journal of cosmetic dermatology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Observational
  3. Using High Frequency Ultrasound to Assess the Efficacy of Anti-Cellulite Treatments.Clinical, cosmetic and investigational dermatology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Alejandra Fernández SantosTermosalud SL, Gijón, Spain.ORCID https://orcid.org/0009-0003-2839-7687
Alejandra Iglesias FernándezTermosalud SL, Gijón, Spain.
Lorena Suárez FernándezTermosalud SL, Gijón, Spain.
Leticia Huergo ZapicoTermosalud SL, Gijón, Spain.ORCID https://orcid.org/0000-0001-9942-1144
Susana Valero FreitagTermosalud SL, Gijón, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAging associated with the passage of time causes alterations in subcutaneous tissues and the overall appearance of the skin that generate aesthetic unconformities in people. Within the wide range of available techniques on the market, radiofrequency (RF) diathermy has emerged as one of the most used non-invasive methods to combat them.

objectiveThis clinical trial aims to determine and quantify the effectiveness and safety of the high-frequency RF-based device Symmed (Termosalud Inc., Gijón, Spain) in cellulite appearance improvement and thigh remodeling treatments. MATERIAL AND

methodsEight sessions of Symmed were performed every 72/96 h in eight subjects' thighs. Safety and effectiveness of the device were evaluated before and after the treatments by digital photographs, body contours measurements, and ultrasound images of skin echogenicity and fat tissue thickness. Information regarding the satisfaction level of the participants was obtained throughout a customized questionnaire.

resultsAfter the treatments, significant reductions of 3% in thighs circumferences (p < 0.05) and 20% in subcutaneous fat layer thickness (p < 0.01) were detected. Dermal echogenicity, used as an indicator of skin organization and collagen content, showed a significant 6% increase (p < 0.05). Before and after photographs revealed a general improvement in skin appearance. The results were complemented by a high satisfaction level (100%) and the absence of adverse events.

conclusionSymmed RF therapy is a non-invasive, safe, effective, and well-tolerated procedure for the treatment of thighs cellulite appearance and body remodeling.

Indexed as

Body ContouringCelluliteCosmetic TechniquesDiathermyRadiofrequency TherapyAdultFemaleHumansMaleMiddle AgedPatient SatisfactionSkinSkin AgingSubcutaneous FatThighTreatment Outcomecellulitecollagenradiofrequencyskin structuresubcutaneous fat

Identifiers

PMID39815666
PMCPMC11735865

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.