Evidence map›Paper›PMID 39815643›Full record

ArticleFuture oncology (London, England)2025

Physician knowledge, use, and perceptions of genetic biomarker testing for the management of patients with newly diagnosed advanced ovarian cancer: an international physician survey.

Susana Banerjee, Ramez N Eskander, Tom Bailey, Will Ambler, Stephanie Volpe, Ozan Özgören, Jacek P Grabowski, Giorgio Valabrega

Abstract read
In one paragraph

Article in Future oncology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Susana BanerjeeGynaecology Unit, The Royal Marsden NHS Foundation Trust and Institute of Cancer Research, London, UK.ORCID 0000-0002-8840-7934
Ramez N EskanderSan Diego Moores Cancer Center, University of California, San Diego, CA, USA.
Tom BaileyAdelphi Real World, Bollington, UK.
Will AmblerAdelphi Real World, Bollington, UK.
Stephanie VolpeGlobal Medical Affairs, Gynecologic Cancers, Oncology R&D, AstraZeneca Pharmaceuticals LP, Cambridge, UK.
Ozan ÖzgörenGlobal Medical Affairs, Gynecologic Cancers, Oncology R&D, AstraZeneca Pharmaceuticals LP, Cambridge, UK.
Jacek P GrabowskiDepartment of Gynecology, Campus Virchow-Klinikum, Charité Medical University Berlin, Berlin, Germany.
Giorgio ValabregaDepartment of Oncology, University of Turin, Division of Medical Oncology, Ordine Mauriziano Hospital, Turin, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo explore physician-reported knowledge, use, and perceptions of genetic testing for advanced ovarian cancer management. MATERIALS &

methodsGynecology/oncology specialists (

resultsPhysician-reported breast cancer gene mutation (BRCAm) testing rates increased over the 2 years before the survey; most patients underwent testing in the preceding 6 months. Homologous recombination deficiency (HRD) genomic instability testing rates and physicians' confidence interpreting results remained relatively low. Genetic testing was driven by the associated treatment implications of the findings. Poor performance status, inadequate tissue, and patients' willingness to undergo testing were reported barriers to testing.

conclusionsFindings indicate that there is a need to improve both access to and information about HRD testing.

Indexed as

Biomarkers, TumorGenetic TestingHealth Knowledge, Attitudes, PracticeOvarian NeoplasmsPhysiciansPractice Patterns, Physicians'AdultAgedFemaleHumansMiddle AgedMutationSurveys and QuestionnairesBiomarkers, TumorBiomarker testingBRCA mutation testinghomologous recombination deficiencyHRD genomic instability testingolaparibovarian cancerPARP inhibitorsphysician survey

Identifiers

PMID39815643
PMCPMC11812359

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.