Evidence map›Paper›PMID 39815397›Full record

ArticleFEBS open bio2025

Evaluation of synaptotagmin-1 action models by all-atom molecular dynamics simulations.

Josep Rizo, Klaudia Jaczynska, Christian Rosenmund

Abstract read
In one paragraph

Article in FEBS open bio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Josep RizoDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID https://orcid.org/0000-0003-1773-8311
Klaudia JaczynskaDepartment of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID https://orcid.org/0000-0003-2113-2320
Christian RosenmundInstitute of Neurophysiology, Charité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Germany.

Funding

Mechanisms of neurotransmitter release and its regulationR35NS097333 · NINDS · UT SOUTHWESTERN MEDICAL CENTER · PI RIZOREY, JOSE · 2017 to 2024
$7.0M
NINDS NIH HHS R35 NS097333Welch Foundation I-1304
6 · The paper itself

Abstract

Neurotransmitter release is triggered in microseconds by the two C

Indexed as

Molecular Dynamics SimulationSynaptotagmin ICalciumCell MembraneHumansLipid BilayersMembrane FusionProtein BindingSNARE ProteinsCalciumLipid BilayersSNARE ProteinsSynaptotagmin Imembrane fusionmolecular dynamics simulationneurotransmitter releaseSNAREssynaptic vesicle fusionsynaptotagmin

Identifiers

PMID39815397
PMCPMC12051017

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.