Evidence map›Paper›PMID 39815138›Full record

ArticleJournal of cancer survivorship : research and practice2026

Perceived cognitive impairment and occupational functioning in prostate cancer survivors: an exploratory cross-sectional analysis.

Lorna Pembroke, Kerry A Sherman, Haryana M Dhillon, Heather Francis, David Gillatt, Howard Gurney

Abstract read
In one paragraph

Article in Journal of cancer survivorship : research and practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Work challenges and cancer-related cognitive impairment: level of education accounts for unmet needs beyond cognitive impairment severity.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lorna PembrokeLifespan Health and Wellbeing Research Centre, Macquarie University, Sydney, NSW, 2109, Australia. lorna.huang@mq.edu.au.ORCID 0000-0002-1666-9855
Kerry A ShermanLifespan Health and Wellbeing Research Centre, Macquarie University, Sydney, NSW, 2109, Australia.ORCID 0000-0001-7780-6668
Haryana M DhillonCentre for Medical Psychology and Evidence-Based Decision-Making, Faculty of Science, School of Psychology, University of Sydney, Sydney, NSW, 2006, Australia.ORCID 0000-0003-4039-5169
Heather FrancisFaculty of Medicine, Health and Human Sciences, School of Psychological Sciences, Macquarie University & Macquarie University Hospital, Sydney, NSW, 2109, Australia.ORCID 0000-0002-7223-7782
David GillattMacquarie University Urology Clinic, Faculty of Medicine and Health Sciences, Macquarie University & Macquarie University Hospital, Sydney, NSW, 2109, Australia.ORCID 0000-0003-4581-9346
Howard GurneyMacquarie University Clinical Trials Unit (CTU), Faculty of Medicine and Health Sciences, Macquarie University & Macquarie University Hospital, Sydney, NSW, 2109, Australia.ORCID 0000-0003-0217-5261

Funding

HPV, HIV and Oral Microbiota Interplay in Nigerian Youth (HOMINY)R01DE032216 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI MODUPE COKER, Nosayaba Osazuwa-Peters · 2022 to 2026
$4.5M
Suicide risk detection and mitigation in patients with head and neck cancerK01DE030916 · NIDCR · DUKE UNIVERSITY · PI OSAZUWA-PETERS, NOSAYABA · 2021 to 2025
$821k
Long-term Opioid Therapy, Depression and Suicide Mortality Risk in Patients with Head and Neck CancerR21DE032531 · NIDCR · DUKE UNIVERSITY · PI OSAZUWA-PETERS, NOSAYABA · 2022 to 2022
$448k
NIDCR NIH HHS K01 DE030916NIDCR NIH HHS R01 DE032216NIDCR NIH HHS R21 DE032531
6 · The paper itself

Abstract

purposePerceived cancer-related cognitive impairment (CRCI) has been reported in prostate cancer survivors. Little is known about how CRCI impacts occupational functioning in working-aged prostate cancer survivors (PCS). This study aimed to investigate the association between CRCI and occupational functioning in PCS.

methodsData from 51 PCS, who were employed at the time of diagnosis, undergoing hormonal treatments (e.g., androgen deprivation therapy) or 'watchful waiting'/ 'active surveillance', were analysed. An online survey assessed CRCI using the FACT-Cog Perceived Cognitive Impairments (PCI20) subscale, the EORTC-QLQ-30 two-item cognitive functioning scale, and a single 'Yes/No' CRCI item (i.e., were 'changes in thinking (e.g., memory, attention)' experienced as a treatment side effect). PCS also indicated 'Yes/No' to changes to their ability to work, performance of work duties, and decreased work hours. Logistic regression analyses examined the relationship between CRCI measures and occupational outcomes.

resultsOf the 51 PCS, 19 (37%) endorsed experiencing cognitive side effects from treatment. The single 'Yes/No' CRCI question was significantly associated with perceived changes in work ability and ability to perform work duties at the same level. PCI20 and the EORTC-QLQ-30 cognitive functioning scale were not significantly associated with any occupational outcomes.

conclusionPerceived CRCI is associated with adverse changes to occupational functioning and is important to consider when PCS are making plans to return-to-work following treatment. IMPLICATIONS FOR CANCER SURVIVORS: Prostate cancer survivors may experience cognitive changes, which may impact their work ability.

Indexed as

Cancer SurvivorsCognitive DysfunctionEmploymentProstatic NeoplasmsAgedCross-Sectional StudiesHumansMaleMiddle AgedQuality of LifeSurveys and QuestionnairesCancer-related cognitive impairmentCognitive functionsOccupational functioningProstate cancerRehabilitationReturn to work

Identifiers

PMID39815138
PMCPMC13375849

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.