ArticleNature2025
Cationic peptides cause memory loss through endophilin-mediated endocytosis.
Abstract read
In one paragraph
Article in Nature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Neuroplastin Suppresses Seizures by Downregulating Endophilin A1 to Promote Internalization of GluA1-AMPA Receptors: Therapeutic Implications of Arbutin.Neuroscience bulletin · 2026Article
- Common themes in evoked ion channel translocation in neuroplastic and homeostatic plasticity.Frontiers in pharmacology · 2026Review
- Bending the boundaries: the many facets of endophilin-As from membrane dynamics to disease.Cellular and molecular life sciences : CMLS · 2025Review
- Novel Lung Cell-Penetrating Peptide Targets Alveolar Epithelial Type II Cells, Basal Cells, and Ionocytes.Pharmaceutics · 2025Article
Corrections and comments
- Update of
Authors and funding
14 authors.
Eric G StokesPharmacology Graduate Program, University of Colorado Anschutz, Aurora, CO, USA.
Jose J VasquezDepartment of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA.ORCID 0000-0002-4922-1520
Ghalia AzouzDepartment of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA.
Megan NguyenDepartment of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA.
Alexa TiernoDepartment of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA.
Yinyin ZhuangDepartment of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA.ORCID 0000-0002-3893-471X
Vivienne Mae GalinatoDepartment of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA.
May HuiDepartment of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA.
Michael ToledanoDepartment of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA.ORCID 0000-0002-1470-9630
Isabella TylerDepartment of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA.ORCID 0000-0003-1721-1333
Xiaoyu ShiDepartment of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA.ORCID 0000-0002-9634-2659
Robert F HuntDepartment of Anatomy and Neurobiology, University of California, Irvine, Irvine, CA, USA.
Jason AotoPharmacology Graduate Program, University of Colorado Anschutz, Aurora, CO, USA.
Kevin T BeierDepartment of Physiology and Biophysics, University of California, Irvine, Irvine, CA, USA. kbeier@uci.edu.ORCID 0000-0002-4934-1338
Funding
Rewiring the Injured Brain with GABA ProgenitorsR01NS096012 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI HUNT, ROBERT F · 2016 to 2025
$3.8MCircuitry dynamics underlying opioid-dependence: Integrating structural, functional, and transcriptomic mechanismsR01DA056599 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI KEVIN T BEIER, Julie A Blendy · 2022 to 2026
$3.8MSculpting the brain: High-resolution spatiotemporally-controlled modulation of memoriesDP2AG067666 · NIA · UNIVERSITY OF CALIFORNIA-IRVINE · PI BEIER, KEVIN T, CORDER, GREGORY · 2019 to 2022
$3.1MGel-based Optical-isolation Single-Cell 3D Spatial MultiomicsDP2GM150017 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SHI, XIAOYU · 2022 to 2025
$2.6MMapping opioid-dependence state transitions across structural, functional, and transcriptomic topologiesR01DA054374 · NIDA · UNIVERSITY OF PENNSYLVANIA · PI BLENDY, JULIE A, CORDER, GREGORY · 2021 to 2025
$2.4MFunctional and mechanistic interrogation of alpha neurexin extracellular domainsR01MH116901 · NIMH · UNIVERSITY OF COLORADO DENVER · PI AOTO, JASON · 2018 to 2022
$1.9MInvestigation of neural ensembles driving pain chronificationR01NS130044 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI KEVIN T BEIER, Gregory Corder · 2023 to 2026
$1.4MINVESTIGATING FUNCTION OF NOVEL DRUG-INDUCED SYNAPTIC CHANGES IN THE VTAR00DA041445 · NIDA · UNIVERSITY OF CALIFORNIA-IRVINE · PI BEIER, KEVIN T · 2018 to 2020
$747kElucidating How Primary Cilia Regulate Hedgehog Signaling by Super-Resolution MicroscopyR00GM126136 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI SHI, XIAOYU · 2020 to 2022
$746kControl of subsynaptic domain organization and nanocolumn alignment by neurexin-3R21MH129620 · NIMH · UNIVERSITY OF COLORADO DENVER · PI AOTO, JASON · 2022 to 2023
$408kInvestigation of neural ensembles underlying chronic painF30DA056215 · NIDA · UNIVERSITY OF CALIFORNIA-IRVINE · PI May Hui · 2022 to 2026
$189kImaging progressive circuit reorganization after traumatic brain injuryF31NS132447 · NINDS · UNIVERSITY OF CALIFORNIA-IRVINE · PI TIERNO, ALEXA MARIE · 2023 to 2025
$134kNIA NIH HHS DP2 AG067666NIDA NIH HHS F30 DA056215NIDA NIH HHS R00 DA041445NIDA NIH HHS R01 DA054374NIDA NIH HHS R01 DA056599NIGMS NIH HHS DP2 GM150017NIGMS NIH HHS R00 GM126136NIMH NIH HHS R01 MH116901NIMH NIH HHS R21 MH129620NINDS NIH HHS F31 NS132447NINDS NIH HHS R01 NS096012NINDS NIH HHS R01 NS130044
Abstract
The zeta inhibitory peptide (ZIP) interferes with memory maintenance and long-term potentiation (LTP)
Indexed as
AcyltransferasesEndocytosisMemory DisordersPeptidesAnimalsBrain InjuriesHippocampusHumansLong-Term PotentiationMaleMemoryMiceMice, Inbred C57BLPinocytosisProtein Kinase CReceptors, AMPA2-acylglycerophosphate acyltransferaseAcyltransferasesPeptidesProtein Kinase CReceptors, AMPA
Identifiers
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Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.