ArticleGeriatric nursing (New York, N.Y.)
Physical function, functional capacity, cognition, and brain structure and function in older adults with chronic kidney disease (CKD).
Article in Geriatric nursing (New York, N.Y.). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveTo evaluate associations between brain structure/function with physical function and functional capacity in older adults with CKD and cognitive complaints.
methodsWe evaluated associations between neuroimaging and cognitive function with functional capacity and physical function in older adults (60-80years) with CKD and cognitive complaints (n = 39; age 67.6 years).
resultsIn multivariable analysis, each standard deviation (SD) increase in 6-minute walk test (6MWT) distance (functional capacity) was associated with better attention/information processing (Trails Making Test-A (TMT-A) (ß -10.86, 95% Confidence Interval (CI) -16.67, -5.06); digit symbol test (ß 5.24, 95% CI 1.02, 9.46)), and each SD increase in short physical performance battery (SPPB)(physical function) was associated with better attention/information processing (TMT-A) (ß -10.99, 95% CI -16.59, -5.39). 6MWT distance and SPPB were associated with some indicators of brain structure/diffusivity.
conclusionIn older adults with CKD and cognitive complaints, functional capacity and physical function may be associated with cognition and brain structure/function.
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