Evidence map›Paper›PMID 39814543›Full record

ArticleJournal of Alzheimer's disease : JAD2025

Associations between potential risk factors and blood-brain barrier water permeability in middle-aged and older adults.

Mervin Tee, Beatriz E Padrela, Margaux Dupeyron, Jiannan Huang, Marcus Low, Simon Konstandin, Klaus Eickel, Matthias Günther, Karolina Minta, Victor R Schinazi and 4 more

Abstract read
In one paragraph

Article in Journal of Alzheimer's disease : JAD, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Mervin TeeSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.ORCID 0000-0002-1037-700X
Beatriz E PadrelaDepartment of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Amsterdam University Medical Center, Location VUmc, Amsterdam, the Netherlands.ORCID 0000-0001-6836-9443
Margaux DupeyronDepartment of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Amsterdam University Medical Center, Location VUmc, Amsterdam, the Netherlands.
Jiannan HuangSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.ORCID 0000-0002-5160-5654
Marcus LowSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.ORCID 0009-0001-2622-0576
Simon KonstandinFraunhofer-Insitute for Digital Medicine MEVIS, Bremen, Germany.ORCID 0000-0002-8143-2221
Klaus EickelFraunhofer-Insitute for Digital Medicine MEVIS, Bremen, Germany.ORCID 0000-0002-5700-2029
Matthias GüntherFraunhofer-Insitute for Digital Medicine MEVIS, Bremen, Germany.ORCID 0000-0002-2650-7956
Karolina MintaFuture Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore.ORCID 0000-0002-3346-5088
Victor R SchinaziFuture Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore.ORCID 0000-0002-2345-2806
Giorgio ColomboFuture Health Technologies, Singapore-ETH Centre, Campus for Research Excellence and Technological Enterprise (CREATE), Singapore.ORCID 0000-0002-0721-594X
Jan PetrHelmholtz-Zentrum Dresden-Rossendorf, Institute of Radiopharmaceutical Cancer Research, Dresden, Germany.ORCID 0000-0002-3201-6002
Henk Jmm MutsaertsDepartment of Radiology and Nuclear Medicine, Amsterdam Neuroscience, Amsterdam University Medical Center, Location VUmc, Amsterdam, the Netherlands.ORCID 0000-0003-0894-0307
Saima HilalSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.ORCID 0000-0001-5434-5635

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Blood-Brain BarrierCapillary PermeabilityAgedBlood PressureBody Mass IndexCerebrovascular CirculationCognitive DysfunctionFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedPermeabilityRisk FactorsAlzheimer's diseasearterial spin labellingarterial transit timecerebral blood flowpermeabilityvascular risk factors

Identifiers

PMID39814543
PMCPMC13066473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.