Evidence map›Paper›PMID 39814140›Full record

Trial reportThe Journal of nutrition2025

Influence of Ambient Temperature on Resting Energy Expenditure in Metabolically Healthy Males and Females.

Sara Henkel, Petra Frings-Meuthen, Christina Diekmann, Martin Coenen, Birgit Stoffel-Wagner, Robert Németh, Dominik Pesta, Sarah Egert

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in The Journal of nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05505240 (Influence of Ambient Temperature on Resting Energy Expenditure of Metabolically Healthy Men and Women), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05505240 nacompletednot on this map

Influence of Ambient Temperature on Resting Energy Expenditure of Metabolically Healthy Men and Women

TypeinterventionalSponsorUniversity of BonnRan2022 to 2023Enrolled32ConditionsResting Energy ExpenditureArmsRespiratory analysis at cold temperature, Respiratory analysis at room temperature, Respiratory analysis at thermoneutral temperature, Respiratory analysis at hot temperature
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Sara HenkelInstitute of Nutritional and Food Sciences, University of Bonn, Bonn, Germany.
Petra Frings-MeuthenGerman Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany.
Christina DiekmannInstitute of Nutritional and Food Sciences, University of Bonn, Bonn, Germany.
Martin CoenenInstitute of Clinical Chemistry and Pharmacology, University Hospital Bonn, Bonn, Germany.
Birgit Stoffel-WagnerInstitute of Clinical Chemistry and Pharmacology, University Hospital Bonn, Bonn, Germany.
Robert NémethInstitute of Medical Biometry, Informatics and Epidemiology (IMBIE), University Hospital Bonn, Bonn, Germany.
Dominik PestaGerman Aerospace Center, Institute of Aerospace Medicine, Cologne, Germany; Medical Faculty, University of Cologne, Cologne, Germany; Center for Endocrinology, Diabetes and Preventive Medicine (CEDP), University Hospital Cologne, Cologne, Germany; Cologne Excellence Cluster on Cellular Stress Responses in Aging-Associated Diseases (CECAD), University of Cologne, Cologne, Germany.
Sarah EgertInstitute of Nutritional and Food Sciences, University of Bonn, Bonn, Germany. Electronic address: s.egert@uni-bonn.de.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt is not yet clear to what extent the physiologic regulatory mechanisms that maintain core body temperature are reflected by changes in resting energy expenditure (REE). Particularly, in indirect calorimetry with a canopy, the effects of short-term temperature exposures have not yet been investigated. This can be of relevance for the determination of REE in practice.

objectivesThis randomized crossover study investigated the influence of a 30-min exposure to 18 °C (cool room temperature), 22 °C (room temperature), 28 °C (thermoneutral zone), and 38 °C (heat) on REE determined by assessing the inhaled oxygen volume and the exhaled carbon dioxide volume via indirect calorimetry on 4 consecutive days.

methodsIn total, 32 metabolically healthy participants [16 males and 16 females, age: 25 ± 3 y, body mass index (BMI): 22.4 ± 1.6 kg/m

resultsLean body mass, ambient temperature, and heart rate were the most important determinants (all P < 0.001) and explained 61.3% of the variance in REE. A multivariate linear mixed model analysis revealed that lean mass (15.87 ± 3.66; P < 0.001) and ambient temperature (P = 0.001) significantly influenced REE. REE significantly differed between 18 and 28 °C (18 °C: +96 ± 24 kcal/24 h; P < 0.001), 22 and 28 °C (22 °C: +73 ± 24 kcal/24 h; P = 0.003), and 18 and 38 °C (18 °C: +57 ± 23 kcal/24 h; P = 0.016).

conclusionsEffects of ambient temperature on REE, especially cold, are detectable after only brief exposure, emphasizing the importance of performing indirect calorimetry with a canopy under controlled environmental conditions. The study was registered at clinicaltrials.gov as NCT05505240 (Influence of Ambient Temperature on Resting Energy Expenditure of Healthy Adults - Full Text View - ClinicalTrials.gov).

Indexed as

Basal MetabolismEnergy MetabolismTemperatureAdultBody Mass IndexBody TemperatureCalorimetry, IndirectCross-Over StudiesFemaleHeart RateHumansMaleYoung Adultambient temperaturebody core temperatureheart frequencyheart rateheatmild coldREEresting energy expenditureresting metabolic rateRMR

Identifiers

PMID39814140
PMCPMC11934286

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.