Evidence map›Paper›PMID 39813789›Full record

ArticleGait & posture2025

Gait during community ambulation and laboratory-based walking in people with mild traumatic brain injury.

Prokopios Antonellis, Jae W Lee, Peter C Fino, Margaret M Weightman, Siting Chen, Margaret E Stojak, Mark E Lester, Carrie W Hoppes, Leland E Dibble, Laurie A King

Abstract read
In one paragraph

Article in Gait & posture, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Prokopios AntonellisDepartment of Neurology, Oregon Health & Science University, Portland, OR, United States.
Jae W LeeDepartment of Neurology, Oregon Health & Science University, Portland, OR, United States.
Peter C FinoDepartment of Health and Kinesiology, University of Utah, Salt Lake City, UT, United States.
Margaret M WeightmanCourage Kenny Research Center-Allina Health, Minneapolis, MN, United States.
Siting ChenSchool of Public Health, Oregon Health & Science University, Portland, OR, United States.
Margaret E StojakDepartment of Neurology, Oregon Health & Science University, Portland, OR, United States.
Mark E LesterDepartment of Physical Therapy, University of Texas Rio Grande Valley, Harlingen, TX, United States.
Carrie W HoppesAdvanced Exposures, Diagnostics, Interventions, and Biosecurity (AEGIS) Program, Joint Base San Antonio-Lackland Air Force Base, TX, United States.
Leland E DibbleDepartment of Physical Therapy & Athletic Training, University of Utah, Salt Lake City, UT, United States.
Laurie A KingDepartment of Neurology, Oregon Health & Science University, Portland, OR, United States. Electronic address: kingla@ohsu.edu.

Funding

Oregon Clinical and Translational Research Institute - The National COVID Cohort Collaborative (N3C)UL1TR002369 · NCATS · OREGON HEALTH & SCIENCE UNIVERSITY · PI Cynthia D Morris, Christopher G. Slatore · 2017 to 2026
$78.4M
NCATS NIH HHS UL1 TR002369
6 · The paper itself

Abstract

backgroundGait impairments are common in individuals with mild traumatic brain injury (mTBI), presenting in the acute phase and often persisting in subtle ways over time. Despite the prominence of laboratory gait evaluations, a comprehensive understanding of gait deficits post-mTBI necessitates the examination of various gait domains in real-world environments. Assessing gait during a community ambulation task (CAT) may capture real-world challenges and influence focused interventions or rehabilitation in individuals with mTBI. RESEARCH QUESTION: The aim of the study was to compare gait performance across independent gait domains in individuals with and without mTBI using wearable sensors during both the CAT and laboratory tasks (i.e., 1-minute walk test). Additionally, associations between the CAT and single- and dual-task walking were investigated.

methodsIn this cross-sectional study, 107 participants, including individuals with mTBI (n = 52) and healthy controls (n = 55), underwent gait assessments during the CAT and 1-minute walk tests (single- and dual-task) using wearable sensors. Four independent gait domains (i.e., gait variability, pace, rhythm, and turning), consisting of thirteen gait variables, were analyzed. Statistical methods included t-tests and partial correlations, adjusted for covariates.

resultsIndividuals with mTBI exhibited gait deficits across multiple gait domains. Specifically, increased gait variability, decreased gait pace and turns post mTBI were seen in the CAT and 1-minute walk tests. Notably, the CAT task exhibited greater gait differences in terms of gait variability and pace compared to the laboratory tasks. Across gait domains, the CAT revealed greater number of correlated measures with dual-task walking compared to single-task walking. SIGNIFICANCE: The community ambulation walking task showed more abnormalities across gait domains compared to laboratory walking tests, highlighting the potential importance of incorporating real-life, community ambulatory tasks into post-mTBI evaluation of mobility.

Indexed as

Brain ConcussionGaitGait Disorders, NeurologicWalkingAdultCase-Control StudiesCross-Sectional StudiesFemaleGait AnalysisHumansMaleMiddle AgedWalk TestYoung AdultCommunity ambulationConcussionGaitInertial sensorsMobilityReal world environment

Identifiers

PMID39813789
PMCPMC12915508

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.