ArticleHospital pediatrics2025
Characterizing Vitamin K Refusal in Term Hospital-Born Infants in Minnesota, 2015-2019.
Article in Hospital pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Oral neonatal vitamin K deficiency bleeding prophylaxis in Switzerland (2018-2024), still valid guidelines for healthy infants.European journal of pediatrics · 2026Article
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Authors and funding
8 authors.
Funding
Abstract
BACKGROUND AND
objectivesSome Minnesota clinicians perceive that the incidence of prophylactic vitamin K refusal is increasing, yet the actual incidence and which populations are most likely to refuse is unknown. Our objective is to identify the incidence of vitamin K refusal and to characterize the maternal-newborn dyads with increased refusal rates.
methodsThis retrospective multi-institution study analyzed vitamin K refusal in newborns born from 2015 to 2019. Maternal-newborn dyad delivery and community characteristics (language, religion, population size) were collected and analyzed by univariable and multivariable logistic regression.
resultsAmong 102 451 term infants, 1.3% did not receive intramuscular vitamin K. Refusal increased from 0.9% in 2015 to 1.6% by 2019 (P < .0001). In multivariable analysis, factors associated with increased likelihood of refusal included female sex (odds ratio [OR] 1.22, 95% CI 1.09-1.36), exclusive human milk feeding at hospital discharge (OR 3.46, 95% CI 2.87-4.17), parity greater than 0 (OR ranging from 1.32 [95% CI 1.13-1.54] for parity of 1, to 3.70 [95% CI 2.80-4.90] for parity of 4), having a midwife at delivery (OR 1.70, 95% CI 1.45-2.01), public insurance (OR 1.84, 95% CI 1.60-2.12), and Russian language (OR 4.92, 95% CI 2.90-8.35). Some religious identities had higher refusal rates (ie, Pentecostal 7.0%, Baptist 3.3%).
conclusionIn a cohort of Minnesota hospital-born infants, the incidence of vitamin K refusal increased between 2015 and 2019. We identified large populations (eg, public insurance, exclusive human milk feeding) and smaller discrete communities (eg, Russian, Pentecostal) with opportunities for increasing prophylactic vitamin K acceptance through targeted community conversations.
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