Evidence map›Paper›PMID 39812852›Full record

ArticleCurrent microbiology2025

Antimicrobial and Cytotoxic Potential of Endophytic Aspergillus versicolor Isolate from the Medicinal Plant Plectranthus amboinicus.

S Manaswini, R Akshata, V Bhoomika, P Nandini, K Ganapathy, K P Deeshma

Abstract read
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Article in Current microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S ManaswiniDepartment of Microbiology and Botany, School of Sciences, J. C. Road, JAIN (Deemed-to-be University), Bangalore, Karnataka, 560027, India.
R AkshataDepartment of Microbiology and Botany, School of Sciences, J. C. Road, JAIN (Deemed-to-be University), Bangalore, Karnataka, 560027, India.
V BhoomikaDepartment of Microbiology and Botany, School of Sciences, J. C. Road, JAIN (Deemed-to-be University), Bangalore, Karnataka, 560027, India.
P NandiniDepartment of Microbiology and Botany, School of Sciences, J. C. Road, JAIN (Deemed-to-be University), Bangalore, Karnataka, 560027, India.
K GanapathyDepartment of Biotechnology and Genetics, School of Sciences, J. C. Road, JAIN (Deemed-to-be University), Bangalore, Karnataka, 560027, India.
K P DeeshmaDepartment of Microbiology and Botany, School of Sciences, J. C. Road, JAIN (Deemed-to-be University), Bangalore, Karnataka, 560027, India. deeshma.kp@gmail.com.ORCID http://orcid.org/0000-0002-3226-6714

Funding

Jain University JU/MRP/SOS/33/2023
6 · The paper itself

Abstract

Endophytic fungi are non-pathogenic organisms that colonise healthy plant tissues asymptomatically. Endophytes derived from medicinal plants are sources for identifying natural products and bioactive compounds with potential uses for industry, medicine, agriculture, and related sectors. In the present study, ethyl acetate crude extracts of four endophytic fungal isolates (CALF1, CALF4, and CASF1) from the medicinal plant Plectranthus amboinicus showed potent antimicrobial activity against the test pathogenic bacteria Escherichia coli, Staphylococcus aureus, Pseudomonas aeruginosa, and Bacillus subtilis using disc diffusion assays. A colorimetric microdilution assay to detect the minimum inhibitory concentration (MIC) revealed that the extracellular extract (ECE) of CASF1 isolate had the lowest MIC values against the test pathogenic bacteria (0.19-6.25 mg/ml) compared to other CALF1 and CALF4. Cytotoxic activity of CASF1-ECE against the drug-resistant KB.CHR.8-5 cancer cell line tested by the MTT assay showed complete cell death at a concentration of 220 μg/mL and the half-maximum inhibitory concentration (IC

Indexed as

Anti-Bacterial AgentsAnti-Infective AgentsAspergillusEndophytesPlants, MedicinalPlectranthusBacteriaCell Line, TumorCell SurvivalEscherichia coliHumansMicrobial Sensitivity TestsAnti-Bacterial AgentsAnti-Infective Agents

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.