Evidence map›Paper›PMID 39812764›Full record

ReviewJournal of assisted reproduction and genetics2025

Current status of fertility preservation procedures in gynecologic oncology: from a Chinese perspective.

Manlin Zhang, Jing Feng, Wenxin Ma, Lin Qiu, Danbo Wang, Zhuo Yang

Abstract readReview
In one paragraph

Review in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Mucinous Ovarian Cancer in a Young Woman: A Case Report.JNMA; journal of the Nepal Medical Association · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Manlin ZhangDepartment of Obstetrics and Gynecology, Shengjing Hospital of China Medical University, Shenyang, China.ORCID http://orcid.org/0009-0006-5797-1491
Jing FengDepartment of Gynaecology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Liaoning Province, Shenyang, 110001, The People's Republic of China.
Wenxin MaDepartment of Gynaecology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Liaoning Province, Shenyang, 110001, The People's Republic of China.
Lin QiuDepartment of Gynaecology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Liaoning Province, Shenyang, 110001, The People's Republic of China.
Danbo WangDepartment of Gynaecology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Liaoning Province, Shenyang, 110001, The People's Republic of China.
Zhuo YangDepartment of Gynaecology, Cancer Hospital of Dalian University of Technology, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Liaoning Province, Shenyang, 110001, The People's Republic of China. yangzhuo@cancerhosp-ln-cmu.com.

Funding

Liaoning Province "Xingliao Talent Program" Medical Experts Project, Young Medical Experts Special Project TXMJ-QN-06Liaoning Provincial Department of Science and Technology, Liaoning Provincial Application-oriented Basic Research Project, Project Name: Research and Application of Metabolic Biomarkers for Early Detection and Prognosis Evaluation of Ovarian Cancer 2022JH2/101300045National Natural Science Foundation of China, Young Scientists Fund Project, Project Name: Identification of Chemotherapy-Induced Resistance Protein Targets in Epithelial Ovarian Cancer and Establishment of a Two-Photon Fluorescence Visualization Monitorin 82103056
6 · The paper itself

Abstract

backgroundThe "Healthy China" initiative, along with advancements in technology for cancer diagnosis and treatment, has significantly enhanced outcomes for patients with gynecologic tumors. The trends of late marriage and delayed childbirth have led to an increasing number of women diagnosed with gynecologic cancers who are seeking fertility preservation in China. This issue is critical yet often overlooked in clinical practice. This review aims to synthesize the existing research on fertility preservation within the field of gynecologic oncology, emphasizing both clinical explorations and expert guidelines.

methodsWe conducted a comprehensive literature review on fertility preservation in the context of gynecologic tumors, examining treatment approaches, commonly employed tumor management technologies, and specific techniques for preserving fertility.

resultsThis extensive review highlights the importance of integrating fertility preservation strategies into treatment plans for gynecologic tumors. It explores various methods to safeguard fertility during chemotherapy, radiation therapy, and surgical interventions. For patients with early-stage cervical cancer, surgical options are available; however, these may result in obstetric complications. Neoadjuvant chemotherapy is currently under investigation as an alternative approach. Endometrial cancer can be managed through hysteroscopic resection combined with hormonal therapy. The feasibility of fertility preservation in ovarian cancer varies based on tumor type and patient age. In cases of vulvar and vaginal cancers, partial excision may be considered following a thorough evaluation. Chemotherapy for gestational trophoblastic tumors has proven effective and typically preserves fertility despite potential decreases in AMH levels.

conclusionThis review provides a comprehensive and current synthesis of the latest evidence and clinical practice guidelines regarding fertility preservation in gynecologic cancers. Its aim is to assist clinicians and researchers in addressing the urgent and increasing demand for effective fertility preservation strategies for their patients.

Indexed as

Fertility PreservationGenital Neoplasms, FemaleChinaEast Asian PeopleFemaleFertilityHumansPregnancyCervical cancerEmbryo freezing technologyEndometrial cancerFertility preservationOvarian cancerOvarian tissue freezing technology

Identifiers

PMID39812764
PMCPMC11871211

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.