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ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2025

Trends in screening and treatment of osteoporosis after periprosthetic fractures from 2010 to 2020.

Jackson W Durbin, Amy Y Zhao, Eric Cui, Amil R Agarwal, Andrew Smith, Alex Gu, Gregory J Golladay, Savyasachi C Thakkar

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jackson W DurbinDepartment of Orthopaedic Surgery, The George Washington University School of Medicine and Health Sciences, 2300 I St NW, Washington, DC, 20052, USA. jackson.durbin@gwmail.gwu.edu.
Amy Y ZhaoDepartment of Orthopaedic Surgery, The George Washington University School of Medicine and Health Sciences, 2300 I St NW, Washington, DC, 20052, USA.
Eric CuiDepartment of Orthopaedic Surgery, The George Washington University School of Medicine and Health Sciences, 2300 I St NW, Washington, DC, 20052, USA.
Amil R AgarwalDepartment of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Andrew SmithDepartment of Orthopaedic Surgery, The George Washington University School of Medicine and Health Sciences, 2300 I St NW, Washington, DC, 20052, USA.
Alex GuDepartment of Orthopaedic Surgery, The George Washington University School of Medicine and Health Sciences, 2300 I St NW, Washington, DC, 20052, USA.
Gregory J GolladayDepartment of Orthopaedic Surgery, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Savyasachi C ThakkarDepartment of Orthopaedic Surgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteoporosis is often underrecognized and undertreated following periprosthetic fractures (PPF). Our study found that between 2010 and 2020, there has been no significant change in the rates of osteoporosis screening or treatment within 1 year following PPF. Orthopedic surgeons can play an integral role in helping to curtail the osteoporosis epidemic. PURPOSE: Periprosthetic fractures (PPF) typically occur from low-energy mechanisms and are pathognomonic for osteoporosis. However, osteoporosis is often underrecognized and undertreated. The aim of this study was to examine trends in dual energy X-ray absorptiometry (DXA) scans and treatment of osteoporosis after PPF between 2010 and 2020.

methodsPatients older than 40 who experienced a lower extremity PPF between 2010 and 2020 and had no prior history of osteoporosis screening or treatment were identified utilizing a large national administrative database. Rates of bone mineral density (BMD) measurement using DXA and anti-osteoporotic treatment with pharmacotherapy, or either intervention within 1 year following experiencing a PPF were determined. The rate of change for these interventions was calculated using the compounded annual growth rate (CAGR), with linear regression used to determine whether trends were statistically significant.

resultsIn total, 5.7% and 3.6% of patients were screened and treated for osteoporosis, respectively. Between 2010 and 2020, there was no significant change in rates of osteoporosis screening (CAGR + 0.1%; p = 0.13), treatment (CAGR - 2.4%; p = 0.29), or either intervention (CAGR - 1.1%; p = 0.77) within 1 year following PPF. Factors associated with intervention included older age, female sex, and increased comorbidities.

conclusionOur study found that there has been no significant change in the rates of osteoporosis screening or treatment within 1 year following PPF. Orthopedic surgeons and allied healthcare workers can play an integral role in helping to curtail the osteoporosis epidemic.

Indexed as

OsteoporosisOsteoporotic FracturesPeriprosthetic FracturesAbsorptiometry, PhotonAgedAged, 80 and overBone DensityBone Density Conservation AgentsDatabases, FactualFemaleHumansMaleMass ScreeningMiddle AgedRetrospective StudiesBone Density Conservation AgentsOsteoporosis epidemicOsteoporosis screeningPeriprosthetic fractures

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.