Evidence map›Paper›PMID 39812662›Full record

ArticleArchives of dermatological research2025

Evaluation of common topical therapeutic agents of plane warts.

Kholod A Ali, Ahmed Rahmah Abu-Raghif, Hayder Ridha-Salman

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Archives of dermatological research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kholod A AliCollege of Medicine, Department of Medicine, Al-Nahrian University, Baghdad, Iraq.
Ahmed Rahmah Abu-RaghifCollege of Medicine, Department of Pharmacology, Al-Nahrian University, Baghdad, Iraq.
Hayder Ridha-SalmanCollege of Pharmacy, Al-Mustaqbal University, 51001, Hillah, Babylon, Iraq. hayder80.ridha@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Management of plane warts is difficult; techniques like cryotherapy and cauterization are linked with a significant number of recurrences, risk of scarring, pain, and costs. To evaluate the effectiveness of TCA 30% solution in comparison with tretinoin 0.05% cream and5-flurouracil (5-FU) 5% cream in treatment of plane wart. A total of 100 patients were haphazardly divided into three groups according to the treatment: 34 patients treated with TCA 30%, 34 patients treated with tretinoin 0.05%, and 32 patients treated with 5-FU 5%. The number of lesions was calculated in all patients before treatment initiation. The efficiency of drugs was evaluated at 6 and 12 weeks after treatment during which the number of the warts in each patient and any side effects associated with the study concoction were recorded. According to the reduction in number of warts, response was categorized in to complete, partial and no response. After 6 weeks' treatment with TCA, Tretinoin and 5-FU, the lesion number reduced to 24%, 70.1% and 68.11% respectively with significant differences between TCA and other two groups. Similarly, after 12 weeks, the lesion number reduced to 14%, 51.67% and 26.86%, respectively with significant differences between TCA and other 2 groups. Additionally, hyper/hypopigmentation was more frequent in TCA treated group than tretinoin and 5-FU groups. Each of TCA, tretinoin and 5-FU are effective in treatment of plane wart, however; TCA seems to be more effective but associated with more pigmentary problems.

Indexed as

FluorouracilTretinoinTrichloroacetic AcidWartsAdministration, CutaneousAdolescentAdultChildFemaleHumansMaleMiddle AgedTreatment OutcomeYoung AdultFluorouracilTretinoinTrichloroacetic Acid5-fluouracilHuman papillomavirusPlane wartSkin diseasesTretinoinTrichloroacetic acid

Identifiers

PMID39812662

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.