ArticleClinical cardiology2025
Health Care Resource Utilization With Dronedarone Versus Sotalol Following Catheter Ablation in Adults With Atrial Fibrillation.
Article in Clinical cardiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- New recommendations for rhythm control-What has changed in the 2023 ACC/AHA/ACCP/HRS and 2024 ESC guidelines for atrial fibrillation, and where does dronedarone fit in?American heart journal plus : cardiology research and practice · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
backgroundClinical trials support dronedarone use for atrial fibrillation (AF) following catheter ablation (CA); however, comparative data on health care resource utilization (HCRU) with other antiarrhythmic drugs are lacking.
methodsRetrospective analysis of Merative MarketScan databases (January 01, 2012-March 31, 2020) comparatively assessed HCRU in US adults with AF who received dronedarone or sotalol post-CA. Patients with ≥ 12-months' pre-CA data were followed from post-CA index treatment to disenrollment, death, or study end. Sotalol-treated patients were propensity score-matched (1:1) with dronedarone-treated patients. Events/100 patient-years (PY) were analyzed by univariate generalized-linear model with Poisson distribution. Cumulative incidence was analyzed over 12 months by Kaplan-Meier methods. Subgroup analyses were conducted by sex and patients new to dronedarone or sotalol during 12 months pre-CA.
resultsDronedarone and sotalol cohorts were successfully matched (n = 1600 each). Prevalence/100-PY for all-cause, cardiovascular (CV)-related, and atrial tachyarrhythmia (ATA)/AF-related HCRU was lower in dronedarone versus sotalol cohort (all p < 0.05). Cumulative incidence for all-cause, CV-related, ATA/AF-related hospitalizations, and pacemaker implantation was lower in dronedarone versus sotalol cohort (all p < 0.05). Incidence of all-cause and CV-related hospitalizations was lower in dronedarone versus sotalol cohorts in females (n = 460) and males (n = 1115) (all p < 0.05) after rematching. Incidence of ATA/AF-related hospitalization was lower in males versus females receiving dronedarone. For patients new to dronedarone or sotalol (n = 549), HCRU results were generally consistent with primary analyses.
conclusionPost-CA dronedarone, versus sotalol, lowered CV-related HCRU in all-comers with AF and in sex subgroups. Findings may contribute to clinical decision making post-CA in patients with AF.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.