Evidence map›Paper›PMID 39812182›Full record

ArticleJournal of the American Geriatrics Society2025

Mortality and Function After Hip Fracture or Pneumonia in People With and Without Dementia.

Lauren J Hunt, R Sean Morrison, Siqi Gan, Edie Espejo, W John Boscardin, Rebecca Rodin, Katherine A Ornstein, Alexander K Smith

Abstract read
In one paragraph

Article in Journal of the American Geriatrics Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lauren J HuntPhilip R. Lee Institute for Health Policy Studies, University of California, San Francisco, California, USA.ORCID 0000-0002-2731-2173
R Sean MorrisonBrookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine, New York, New York, USA.
Siqi GanNorthern California Institute for Research and Education, San Francisco, California, USA.
Edie EspejoNorthern California Institute for Research and Education, San Francisco, California, USA.
W John BoscardinDepartment of Epidemiology and Biostatistics, University of California, San Francisco, California, USA.
Rebecca RodinBrookdale Department of Geriatrics and Palliative Medicine, Icahn School of Medicine, New York, New York, USA.
Katherine A OrnsteinSchool of Nursing, Johns Hopkins University, Baltimore, Maryland, USA.
Alexander K SmithDivision of Geriatrics, University of California, San Francisco, California, USA.

Funding

HRS Yrs29-34: Y33 SSA CoFundingU01AG009740 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Jessica Faul, KENNETH M LANGA · 1990 to 2026
$555.8M
Residing in the Community with Dementia at the End of Life: Understanding Hospice Use and Residential SettingP30AG028741 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ORNA INTRATOR · 2010 to 2026
$21.9M
VARC CoreP30AG044281 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 2013 to 2026
$19.9M
Unnecessary and Harmful Medication Use in Older Adults with DementiaP01AG066605 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI MELISSA Diane ALDRIDGE · 2020 to 2026
$17.7M
Advanced-Stage Development of a Geriatric Palliative Care Research InfrastructureR33AG065726 · NIA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI ALDRIDGE, MELISSA DIANE, MORRISON, R. SEAN · 2020 to 2024
$3.4M
Mentoring Researchers in Prognosis Research in Alzheimer’s Disease and Related DementiasK24AG068312 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Alexander Keliimoeanu Smith · 2020 to 2026
$1.2M
Hospice Use in Older Adults with Alzheimer's Disease and Related Dementias: Patterns, Policies, and Caregiver ExperiencesK76AG074924 · NIA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI HUNT, LAUREN · 2021 to 2025
$1.1M
NIA NIH HHS K24 AG068312NIA NIH HHS K24AG068312NIA NIH HHS K76 AG074924NIA NIH HHS K76AG074924NIA NIH HHS P01 AG066605NIA NIH HHS P01AG066605NIA NIH HHS P30AG028741NIA NIH HHS P30AG04428NIA NIH HHS P30 AG044281NIA NIH HHS R33AG065726NIA NIH HHS U01AG009740
6 · The paper itself

Abstract

backgroundThe extent to which disruptive surgical or medical events impact mortality and function is critical for anticipatory planning and informing goal-aligned care.

methodsUsing Health and Retirement Study data (2008-2018), we employed propensity score matching to compare the impact of hospitalization for hip fracture (a surgical event) or pneumonia (a medical event) among people with dementia to two groups: (1) people with dementia who did not experience these events; and (2) people without dementia who experienced an event. Dementia status was determined using validated cognitive assessments (Hurd method); hip fracture and pneumonia were identified from Medicare claims. Outcomes were 1-year mortality and function, defined as a summary score of requiring assistance with 6 ADL's and 5 IADL's, with higher scores indicating better function.

resultsAmong people with dementia, predicted 1-year mortality was higher among those with hip fracture (35.4%) versus those without hip fracture (14.8%), with similar patterns for pneumonia (49.6% vs. 13.0%). Among people with dementia, function declined abruptly at time of hip fracture (-2.09 [95% CI -2.94, -1.25]) and continued to decline after (-0.48 [95% CI -0.87, -0.09]). There were similar patterns for pneumonia (drop at time of pneumonia of -1.49 [95% CI -2.0, -0.97] and after -0.05 [95% CI, -0.29, 0.19]). Compared to people without dementia with hip fracture, people with dementia had higher 1-year mortality (35.4%) versus people without dementia (24%), with similar patterns for pneumonia (49.6% vs. 39.7%). Function stabilized for people without dementia after hip fracture (-0.03, 95% CI -0.22, 0.16), which was significantly different than people without dementia (p < 0.0001). Function improved for people without dementia after pneumonia (0.13, 95% CI 0.03, 0.24), but was not statistically different than for people with dementia (p = 0.17).

conclusionDisruptive events such as hip fracture or pneumonia substantially alter the clinical trajectories of people with dementia.

Indexed as

DementiaHip FracturesPneumoniaActivities of Daily LivingAgedAged, 80 and overFemaleHospitalizationHumansMaleMedicarePropensity ScoreUnited Statesacute eventsdementiafunctionmortality

Identifiers

PMID39812182
PMCPMC12981159

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.