Evidence map›Paper›PMID 39811865›Full record

ArticleJournal of education and health promotion2024

Precision medicine and patient outcomes in intensive care unit: Culture sensitivity, antibiotics, and APACHE score IV.

Sidra Zubair, Subia Jamil, Sakina Fatima, Syed T Sibtain, Hira Raees, Asma Eraj, Amber Nawab

Abstract read
In one paragraph

Article in Journal of education and health promotion, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sidra ZubairDepartment of Pharmacology, Faculty of Pharmacy, Jinnah University for Women, Karachi, Sindh, Pakistan.
Subia JamilDepartment of Pharmacology, Faculty of Pharmacy, Jinnah University for Women, Karachi, Sindh, Pakistan.
Sakina FatimaDepartment of Pharmaceutics, Institute of Pharmaceutical Sciences, Jinnah Sindh Medical University, Karachi, Sindh, Pakistan.
Syed T SibtainResident Medical Officer, Department of Medicine, Aga Khan University Hospital, Karachi, Sindh, Pakistan.
Hira RaeesDepartment of Pharmacology, Faculty of Pharmacy, Jinnah University for Women, Karachi, Sindh, Pakistan.
Asma ErajDepartment of Pharmacology, Faculty of Pharmacy, Jinnah University for Women, Karachi, Sindh, Pakistan.
Amber NawabDepartment of Pharmaceutics, Faculty of Pharmacy, Jinnah University for Women, Karachi, Pakistan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn the intensive care unit (ICU), complex medical conditions require specialized care; the threat of antibiotic resistance is significant due to frequent antibiotic use. This study investigates the pivotal role of culture sensitivity testing in shaping antibiotic prescription practices and patient outcomes in ICUs. MATERIALS AND

methodsBy using a prospective observational-analytical design, medical data from 640 patients at a Karachi hospital for one year in 2022 were utilized. The study focused on antibiotic therapy, including empiric and targeted approaches, culture sensitivity testing, the use of the APACHE scale for mortality prediction, and changes in antibiotic regimens based on culture reports. Statistical analysis involved Fisher's Exact and ANOVA tests.

resultThe age category above 60 emerged with the highest survivorship. Contrary to expectations, age did not seem to correlate significantly with mortality rates.

conclusionsComplex antibiotic combinations were prescribed for broad clinical conditions. These insights pave the way for future research on antibiotic stewardship in ICUs, navigating more effective and targeted treatments.

Indexed as

Antibiotic stewardshipAPACHE score IVculture sensitivityintensive care unitmicroorganisms

Identifiers

PMID39811865
PMCPMC11731236

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.