Evidence map›Paper›PMID 39811760›Full record

ArticleJID innovations : skin science from molecules to population health2025

Reconstructed Epidermis Produced with Atopic Dog Keratinocytes Only Exhibit Skin Barrier Defects after the Addition of Proinflammatory and Allergic Cytokines.

Daniel Combarros, Rahma Brahmi, Emma Musaefendic, Alizée Heit, Jevgenija Kondratjeva, Fabien Moog, Charline Pressanti, Line A Lecru, Sabine Arbouille, Catherine Laffort and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JID innovations : skin science from molecules to population health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. IL-31/33 Axis in Atopic Dermatitis.International journal of molecular sciences · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Daniel CombarrosSmall Animal Clinic, École Nationale Vétérinaire de Toulouse, University of Toulouse, Toulouse, France.
Rahma BrahmiToulouse Institute for Infectious and Inflammatory Diseases (Infinity), University of Toulouse, INSERM, CNRS, Paul Sabatier Toulouse III University, Toulouse, France.
Emma MusaefendicToulouse Institute for Infectious and Inflammatory Diseases (Infinity), University of Toulouse, INSERM, CNRS, Paul Sabatier Toulouse III University, Toulouse, France.
Alizée HeitToulouse Institute for Infectious and Inflammatory Diseases (Infinity), University of Toulouse, INSERM, CNRS, Paul Sabatier Toulouse III University, Toulouse, France.
Jevgenija KondratjevaSmall Animal Clinic, École Nationale Vétérinaire de Toulouse, University of Toulouse, Toulouse, France.
Fabien MoogSmall Animal Clinic, École Nationale Vétérinaire de Toulouse, University of Toulouse, Toulouse, France.
Charline PressantiSmall Animal Clinic, École Nationale Vétérinaire de Toulouse, University of Toulouse, Toulouse, France.
Line A LecruClinique vétérinaire Hermes-Plage, Marseille, France.
Sabine ArbouilleClinique Vet in the Moon, Mont-de-Marsan, France.
Catherine LaffortClinique vétérinaire Alliance, Bordeaux, France.
Dominique GoudounècheCentre de Microscopie Electronique Appliquée à la Biologie, University of Toulouse, Toulouse, France.
Jessie BrunSmall Animal Clinic, École Nationale Vétérinaire de Toulouse, University of Toulouse, Toulouse, France.
Michel SimonToulouse Institute for Infectious and Inflammatory Diseases (Infinity), University of Toulouse, INSERM, CNRS, Paul Sabatier Toulouse III University, Toulouse, France.
Marie-Christine CadierguesSmall Animal Clinic, École Nationale Vétérinaire de Toulouse, University of Toulouse, Toulouse, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Our objectives were to explore epidermal barrier defects in dogs with atopic dermatitis and to determine whether the defects are genetically determined or secondary to skin inflammation. First, the expression of filaggrin, corneodesmosin, and claudin1, analyzed using indirect immunofluorescence in skin biopsies collected from 32 healthy and 32 dogs with atopic dermatitis, was weaker in the atopic skin (

Indexed as

Atopic dermatitisDogInflammationModelSkin barrier

Identifiers

PMID39811760
PMCPMC11730559

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.