Evidence map›Paper›PMID 39811557›Full record

ArticleERJ open research2025

Repeat expansions in

Barnaby Hirons, Peter S P Cho, Katie Rhatigan, Joe Shaw, Riccardo Curro, Bianca Rugginini, Natalia Dominik, Richard D Turner, Ewan Mackay, James H Hull and 6 more

Abstract read
In one paragraph

Article in ERJ open research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Barnaby HironsCentre for Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.ORCID https://orcid.org/0000-0002-5049-6820
Peter S P ChoCentre for Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.ORCID https://orcid.org/0000-0001-8689-8541
Katie RhatiganCentre for Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.
Joe ShawNHS North Thames Genomic Laboratory Hub, London, UK.
Riccardo CurroDepartment of Neuromuscular Disease, UCL Queen Square Institute of Neurology, London, UK.
Bianca RuggininiDepartment of Neuromuscular Disease, UCL Queen Square Institute of Neurology, London, UK.
Natalia DominikDepartment of Neuromuscular Disease, UCL Queen Square Institute of Neurology, London, UK.
Richard D TurnerSchool of Medicine and Dentistry, Griffith University, Southport, Australia.ORCID https://orcid.org/0000-0002-3024-6971
Ewan MackayDepartment of Respiratory Medicine, King's College Hospital, London, UK.
James H HullDepartment of Respiratory Medicine, Royal Brompton Hospital, London, UK.ORCID https://orcid.org/0000-0003-4697-1526
Hisham Abubakar-WaziriDepartment of Respiratory Medicine, Royal Brompton Hospital, London, UK.
Harini KesavanDepartment of Respiratory Medicine, King's College Hospital, London, UK.
Caroline J JolleyCentre for Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.ORCID https://orcid.org/0000-0003-3538-2451
Robert D HaddenDepartment of Neurology, King's College Hospital, London, UK.
Andrea CorteseDepartment of Neuromuscular Disease, UCL Queen Square Institute of Neurology, London, UK.
Surinder S BirringCentre for Human and Applied Physiological Sciences, School of Basic and Medical Biosciences, Faculty of Life Sciences and Medicine, King's College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Refractory chronic cough (RCC), persisting despite addressing contributory diagnoses, is likely underpinned by neurally mediated cough hypersensitivity. Methods: Consecutive patients with RCC underwent Results: 51 participants with RCC were recruited; 36 (71%) female, median (IQR) age 65 (56-70) years, duration of cough 12.8 (6.9-20.0) years. Four (8%) were RFC1 Conclusion: Biallelic RFC1 repeat expansions (RFC1

Identifiers

PMID39811557
PMCPMC11726589

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.