ArticleOphthalmology science
Decreased Choriocapillaris Vessel Density in the Ipsilateral Eye after Carotid Artery Revascularization Detected by Widefield Swept-Source OCT Angiography.
Article in Ophthalmology science. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Interocular asymmetry of fundus characteristics in patients with unilateral severe carotid artery stenosis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Association of retinal microvascular abnormalities with cardiovascular diseases in patients with severe carotid artery stenosis.International journal of medical sciences · 2026Observational
- Retinal Ischemic Perivascular Lesions Are Associated with Cardiovascular Diseases in Patients with Severe Carotid Artery Stenosis.Journal of clinical medicine · 2025Article
- Detection of macular and peripheral ocular microvascular changes after carotid artery revascularization using widefield SS-OCTA.Frontiers in medicine · 2025Article
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9 authors.
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Abstract
Objective: To investigate the short-term blood flow changes and image features of the retina and choroid in patients who underwent carotid artery revascularization (CAR) for severe carotid artery stenosis using widefield swept-source OCT angiography (OCTA). Design: Prospective study. Participants: This prospective study included 112 eyes (56 eyes on the ipsilateral side and 56 eyes on the contralateral side) of 56 participants with severe carotid artery stenosis. Methods: Participants were examined using widefield swept-source OCTA covering an area of 16 × 16 mm centered on the fovea before and after CAR. Retinal parameters including central macular thickness, vessel density of the retinal superficial vascular complex (VDRSVC), vessel density of the retinal deep vascular complex, and vessel density of the retina (VDR) and choroidal parameters, including central choroidal thickness (CCT), vessel density of the choriocapillaris (VDCC), vessel density of the medium and large choroidal vessels, choroidal vessel volume ratio (CVV/a), and 3-dimensional choroidal vascularity index (3D-CVI) were measured. Besides, preoperative and postoperative OCTA images were screened and compared. Main Outcome Measures: Retinal and choroidal parameters obtained from swept-source OCTA. Results: In the ipsilateral eye (56 eyes), an increase in VDRSVC, VDR, CVV/a, CCT, and 3D-CVI and a decrease in VDCC was found after CAR. Thirteen patients were identified with postoperative ipsilateral choriocapillaris flow voids (PICCFVs) with OCTA images, and the presence of PICCFVs was associated with greater postoperative VDCC decrease. In the contralateral eye (56 eyes), we found an increase in VDRSVC, vessel density of the retinal deep vascular complex, and VDR, whereas no difference in choroidal parameters after CAR and no findings of PICCFVs were found. Conclusions: The findings of this study suggest that ocular microvascular perfusion is improved after CAR in the ipsilateral eye and the contralateral eye within a wide field of the fundus. The VDCC is decreased in the ipsilateral eye, which may indicate infarctions of choriocapillaris or ischemia-reperfusion injury of the choriocapillaris after CAR. Financial Disclosures: Proprietary or commercial disclosure may be found in the Footnotes and Disclosures at the end of this article.
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