Evidence map›Paper›PMID 39811246›Full record

ArticleBioactive materials2025

Mechanically robust surface-degradable implant from fiber silk composites demonstrates regenerative potential.

Wenhan Tian, Yuzeng Liu, Bo Han, Fengqi Cheng, Kang Yang, Weiyuan Hu, Dongdong Ye, Sujun Wu, Jiping Yang, Qi Chen and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioactive materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Wenhan TianSchool of Materials Science and Engineering, Beihang University, Beijing, 100191, PR China.
Yuzeng LiuDepartment of Orthopedics, Capital Medical University Affiliated Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, PR China.
Bo HanDepartment of Orthopedics, Capital Medical University Affiliated Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, PR China.
Fengqi ChengDepartment of Orthopedics, Capital Medical University Affiliated Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, PR China.
Kang YangSchool of Materials Science and Engineering, Anhui University of Technology, Maanshan, Anhui, 243002, PR China.
Weiyuan HuSchool of Materials Science and Engineering, Beihang University, Beijing, 100191, PR China.
Dongdong YeCollege of Light Textile Engineering and Art, Anhui Agricultural University, Hefei, Anhui, 230036, PR China.
Sujun WuSchool of Materials Science and Engineering, Beihang University, Beijing, 100191, PR China.
Jiping YangSchool of Materials Science and Engineering, Beihang University, Beijing, 100191, PR China.
Qi ChenNingbo Regen Biotech Co., Ltd., Ningbo, Zhejiang, 315157, PR China.
Yong HaiDepartment of Orthopedics, Capital Medical University Affiliated Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, PR China.
Robert O RitchieDepartment of Materials Science & Engineering, University of California, Berkeley, CA, 94720, USA.
Guanping HeDepartment of Orthopedics, Capital Medical University Affiliated Beijing Chaoyang Hospital, Capital Medical University, Beijing, 100020, PR China.
Juan GuanSchool of Materials Science and Engineering, Beihang University, Beijing, 100191, PR China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Through millions of years of evolution, bones have developed a complex and elegant hierarchical structure, utilizing tropocollagen and hydroxyapatite to attain an intricate balance between modulus, strength, and toughness. In this study, continuous fiber silk composites (CFSCs) of large size are prepared to mimic the hierarchical structure of natural bones, through the inheritance of the hierarchical structure of fiber silk and the integration with a polyester matrix. Due to the robust interface between the matrix and fiber silk, CFSCs show maintained stable long-term mechanical performance under wet conditions. During

Indexed as

Cell-mediated degradationContinuous fiber silkHierarchical structureMacrophage polarizationRegenerative biomaterial

Identifiers

PMID39811246
PMCPMC11732114

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.