ArticleCureus2024
Study of Outcomes of Mucormycosis in COVID-19 Patients at a Tertiary Care Hospital in Central India: A Retrospective Study.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background The COVID-19 pandemic has posed unprecedented challenges to the global healthcare system. Among the various complications, mucormycosis, a fungal infection caused by the Mucorales order, has emerged as a significant threat, particularly in immunocompromised individuals. This study aims to evaluate the outcomes of mucormycosis in COVID-19 patients treated at a tertiary care hospital in Central India. Method This retrospective study reviewed the medical records of 72 patients diagnosed with mucormycosis following COVID-19 infection between April 2021 and July 2021 at the tertiary care hospital. Data on demographics, clinical features, comorbidities, treatment received (surgery, antifungal medications), and treatment outcomes (mortality, response to treatment) were collected and analyzed. Results The mean age of patients was 55.42±12.31 years, with a male predominance (n=44; 61.11%). Facial pain (n=61; 84.72%) and headache (n=58; 80.55%) were the most common clinical features. The mean duration of symptoms was 14.31±5.4 days. Steroids were used in the majority of the patients (n=50; 69%). The most common comorbidity was diabetes mellitus (n=42; 58.33%). Out of 72 patients, 40 (55.6%) survived and 32 (44.4%) patients died. Surgical debridement was performed in 45 (62.5%) patients. All 72 patients (100%) received amphotericin B, an antifungal medication. The older age and lack of early surgical intervention were significant factors associated with higher mortality in patients with mucormycosis in COVID-19. Conclusion This retrospective study reinforces the critical role of early diagnosis, immediate systemic antifungal therapy, stringent management of comorbidities, and prompt surgical intervention in improving outcomes for mucormycosis in COVID-19 patients.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.