ArticleCureus2024
Utilization of High-Flow Nasal Cannulas in Pediatric Critical Care: A Single-Center Experience.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundHigh-flow nasal cannula (HFNC) therapy has developed as a valuable tool for respiratory support in pediatric critical care. It offers an intermediate level of support between traditional low-flow oxygen and non-invasive ventilation (NIV). Studies suggest its effectiveness in improving oxygen delivery, work of breathing, and secretion clearance.
methodThis retrospective study reviewed medical records of 265 pediatric patients aged between one day to 14 years admitted to the pediatric intensive care unit (PICU) for respiratory distress between 2014 and 2019, who required HFNC therapy. Analyzed data on demographics, diagnoses, HFNC settings, physiologic parameters, complications, and outcomes (e.g., escalation of support, length of stay) using IBM SPSS Statistics software, version 23 (IBM Corp., Armonk, NY).
resultsAge, indication, and positive viral nasopharyngeal swabs (NPA) didn't influence the outcome of HFNC. The most common primary admission diagnosis was pneumonia (38.5%); other indications for HFNC treatment included septic shock, pleural effusion, and upper airway obstruction. However, low durations of HFNC, elevated carbon dioxide (CO2), no improvement in potential of hydrogen (pH) after initiation of therapy, and elevated respiratory rate were observed more in the failure group.
conclusionHigh-flow nasal cannula therapy emerges as a valuable alternative to invasive ventilation in PICU patients. Blood gases, respiratory rate, and heart rate (HR) are important parameters, besides clinical examination, to closely monitor the children susceptible to failure.
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