Evidence map›Paper›PMID 39811176›Full record

ArticleThe Iowa orthopaedic journal2024

Efficacy of Intraoperative Intra-Articular Morphine on Post-Operative Pain and Opioid Consumption Following Hip Arthroscopy.

Steele McCulley, Jace Lapierre, Irving Delgado-Arellanes, Joseph Rund, Courtney Seffker, Qiang An, Robert W Westermann

Abstract read
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Article in The Iowa orthopaedic journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Steele McCulleyDepartment of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Jace LapierreDepartment of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Irving Delgado-ArellanesDepartment of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Joseph RundDepartment of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Courtney SeffkerDepartment of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Qiang AnDepartment of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.
Robert W WestermannDepartment of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, Iowa, USA.

Funding

Iowa Medical Student Summer Research Program in trans-NIDDK ResearchT35DK135446 · NIDDK · UNIVERSITY OF IOWA · PI ROBERT D ROGHAIR · 2023 to 2026
$418k
NIDDK NIH HHS T35 DK135446
6 · The paper itself

Abstract

Background: The use of intraoperative intra-articular morphine has been suggested to lower postoperative pain scores and opioid use. We sought to evaluate the effectiveness of intra-articular morphine with 0.75% ropivacaine when compared to the use of ropivacaine alone. Our study's purpose was to determine the efficacy of intra-articular morphine on pain control, opioid consumption, and discharge times in the immediate post-operative period. Methods: We retrospectively reviewed the charts of 100 patients who underwent hip arthroscopy with repair for femoroacetabular impingement (FAI) between 2021 to 2023. 50 patients who received 5 mg of intra-articular morphine injections intraoperatively were identified, and 50 who did not. Patients undergoing hip arthroscopy without repair, revision surgery, or combined hip arthroscopy and femoral osteotomy or periacetabular osteotomy were excluded. Demographics including age, sex, race, ethnicity, BMI, and tobacco use were recorded. Procedural factors included total operative time, traction time, and time to discharge. Pain scores were assessed using the Visual Analog Scale (VAS), and the initial Post-Anesthesia Care Unit (PACU) and final VAS score prior to discharge were recorded. Total acute opioid use was recorded using morphine milligram equivalents (MME) during post-operation to discharge. We used the Wilcoxon rank sum test and chi-square statistics on continuous and categorical variables, respectively. Statistically significant level was set as p<0.05. Results: No significant differences were found between demographics, operative time, traction time, or discharge time. The median age of patients in the non-morphine group was 29 (48% M, 52% F) and 24.5 (34% M, 66% F) in the morphine group. Differences between the morphine and non-morphine group in postoperative VAS scores were insignificant, with the mean initial PACU VAS scores (4.6 ± 3.0 vs 5.5 ± 3.0) and mean final PACU VAS scores (3.5 ± 1.9 vs 3.7 ± 1.4) respectively. Postoperative MME consumption difference was also insignificant (17.1 ± 7.4 vs 17.9 ± 7.3). Conclusion: Intraoperative intra-articular morphine injection with ropivacaine does not provide a significant reduction in acute postoperative pain scores or opioid use when compared to ropivacaine use alone. Further investigation into the efficacy of intra-articular morphine is warranted.

Indexed as

Analgesics, OpioidArthroscopyFemoracetabular ImpingementHip JointMorphinePostoperative PainAdultAnesthetics, LocalFemaleHumansInjections, Intra-ArticularIntraoperative CareMaleMiddle AgedPain MeasurementRetrospective StudiesAnalgesics, OpioidAnesthetics, LocalMorphineRopivacainehip arthroscopyintra-articular injectionlocal anesthetic infiltrationpain management

Identifiers

PMID39811176
PMCPMC11726484

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.