Evidence map›Paper›PMID 39811095›Full record

ReviewExploratory research in clinical and social pharmacy2025

High alert medications off the radar: A systematic review.

Michelle Santos Menezes, Fernanda Valença-Feitosa, Aline Santana Góes, Millena Rakel Dos Santos, Laila Santana Silva, Sylmara Nayara Pereira Dos Santos, Divaldo Pereira de Lyra, Alfredo Dias de Oliveira Filho

Abstract readReview
In one paragraph

Review in Exploratory research in clinical and social pharmacy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Michelle Santos MenezesLaboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, Av. Marcelo Déda Chagas, São Cristóvão, Sergipe, Brazil.
Fernanda Valença-FeitosaLaboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, Av. Marcelo Déda Chagas, São Cristóvão, Sergipe, Brazil.
Aline Santana GóesLaboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, Av. Marcelo Déda Chagas, São Cristóvão, Sergipe, Brazil.
Millena Rakel Dos SantosLaboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, Av. Marcelo Déda Chagas, São Cristóvão, Sergipe, Brazil.
Laila Santana SilvaLaboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, Av. Marcelo Déda Chagas, São Cristóvão, Sergipe, Brazil.
Sylmara Nayara Pereira Dos SantosLaboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, Av. Marcelo Déda Chagas, São Cristóvão, Sergipe, Brazil.
Divaldo Pereira de LyraLaboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, Av. Marcelo Déda Chagas, São Cristóvão, Sergipe, Brazil.
Alfredo Dias de Oliveira FilhoLaboratory of Teaching and Research in Social Pharmacy (LEPFS), Department of Pharmacy, Federal University of Sergipe, Av. Marcelo Déda Chagas, São Cristóvão, Sergipe, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To identify new drugs that present an increased risk of causing significant damage to critically ill patients due to failure in the administration process. Method: The systematic literature review was conducted in the PubMed, Lilacs, Scopus, Web of Science and gray literature. The year in which the study was conducted was not restricted. Results: The initial search in the databases identified 1477 studies. Fifty manuscripts were selected for evaluation of the full text, at the end of which seven articles were included in this systematic review. As for the characteristic of medication errors, the highest frequency occurred in the administration and prescription phases. In all included studies, incidents with drugs that led to damage were observed. The drugs that are not included in the official lists as High Alert Medications (HAM) that presented an increased risk of causing damage due to medication errors found were: risperidone and piperacycline + tazobactan, in addition to the Infectious Agent class. Conclusion: The results revealed that in fact there are drugs not listed as HAM that, when used in errors, promote greater risks of generating damage in critically ill patients. These described drugs should be considered for inclusion in future official lists of HAM.

Indexed as

Critical patientDamageMedication errors

Identifiers

PMID39811095
PMCPMC11731267

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.