Evidence map›Paper›PMID 39811023›Full record

ArticleNanoscale advances2025

Optimal size and PEG coating of gold nanoparticles for prolonged blood circulation: a statistical analysis of published data.

Dmitry Nevozhay, Ronald Rauch, Zhongya Wang, Konstantin V Sokolov

Abstract read
In one paragraph

Article in Nanoscale advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dmitry NevozhayDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center Houston TX 77030 USA dnevozhay@mdanderson.org ksokolov@mdanderson.org.ORCID https://orcid.org/0000-0003-3887-6481
Ronald RauchDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center Houston TX 77030 USA dnevozhay@mdanderson.org ksokolov@mdanderson.org.ORCID https://orcid.org/0009-0003-1005-3587
Zhongya WangDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center Houston TX 77030 USA.ORCID https://orcid.org/0000-0002-3866-8052
Konstantin V SokolovDepartment of Imaging Physics, The University of Texas MD Anderson Cancer Center Houston TX 77030 USA dnevozhay@mdanderson.org ksokolov@mdanderson.org.ORCID https://orcid.org/0000-0002-0198-2005

Funding

In situ cancer cell specific biomineralization to overcome nanoparticle delivery barriers and sensitize pancreatic cancer to radiotherapyR01CA274415 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Sang Hyun Cho, Sunil Krishnan · 2022 to 2026
$3.0M
NCI NIH HHS R01 CA274415
6 · The paper itself

Abstract

This study presents a statistical analysis of how gold nanoparticle (GNP) size and polyethylene glycol (PEG) coating molecular weight (MW) affect the circulation of nanoparticles in blood. We showed a non-linear relationship with interaction between GNP size and PEG MW. The findings revealed a threshold effect, and recommendations for GNP coating are discussed.

Identifiers

PMID39811023
PMCPMC11726233

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.