Evidence map›Paper›PMID 39810856›Full record

ArticleAntimicrobial stewardship & healthcare epidemiology : ASHE2025

Blood culture bottle shortage mitigation efforts: analysis of impact on ordering and patient impact.

Christopher D Doern, Melissa Whitman, Michelle Doll, Suzanne Lavoie, David Friedel, Gonzalo Bearman, Jeffrey Kim, Heather Masters, Susan Roseff, Jim Willis and 9 more

Abstract read
In one paragraph

Article in Antimicrobial stewardship & healthcare epidemiology : ASHE, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. The Impact of a Nationwide Blood Culture Bottle Shortage in 2024 on Healthcare Facilities in the United States.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Christopher D DoernDepartment of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.ORCID https://orcid.org/0000-0003-2454-4355
Melissa WhitmanDepartment of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.ORCID https://orcid.org/0009-0002-3721-8647
Michelle DollDepartment of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.ORCID https://orcid.org/0000-0003-2477-1240
Suzanne LavoieDepartment of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.ORCID https://orcid.org/0009-0009-7334-2304
David FriedelDepartment of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.ORCID https://orcid.org/0000-0001-6936-9082
Gonzalo BearmanDepartment of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Jeffrey KimDepartment of Family Medicine and Population Health, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Heather MastersDepartment of Internal Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Susan RoseffDepartment of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Jim WillisVirginia Commonwealth University Health System, Richmond, VA, USA.
Roxanne MercerVirginia Commonwealth University Health System, Richmond, VA, USA.
Aaron HillVirginia Commonwealth University Health System, Richmond, VA, USA.
Ramana FeeserDepartment of Emergency Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Harinder DhindsaDepartment of Emergency Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.ORCID https://orcid.org/0009-0000-2295-3353
Frank PetruzellaDepartment of Pediatrics, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Anne JacksonVirginia Commonwealth University Health System, Richmond, VA, USA.
Michael VittoDepartment of Emergency Medicine, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.
Josh PlaunyVirginia Commonwealth University Health System, Richmond, VA, USA.
Alexandra BrysonDepartment of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective design: In June of 2024, Becton Dickinson experienced a blood culture bottle shortage for their BACTEC system, forcing health systems to reduce usage or risk exhausting their supply. Virginia Commonwealth University Health System (VCUHS) in Richmond, VA decided that it was necessary to implement austerity measures to preserve the blood culture bottle supply. Setting: VCUHS includes a main campus in Richmond, VA as well as two affiliate hospitals in South Hill, VA (Community Memorial Hospital (CMH)) and Tappahannock Hospital in Tappahannock, VA. It also includes a free-standing Emergency Department in New Kent, VA. Patients: Blood cultures from both pediatric and adult patients were included in this study. Interventions: VCUHS intervened to decrease blood culture utilization across the entire health system. Interventions included communication of blood culture guidance as well as an electronic health record order designed to guide providers and discourage wasteful ordering. Results: Post-implementation analyses showed that interventions reduced overall usage by 35.6% ( Conclusions: These findings strongly suggest that some basic stewardship interventions can significantly change blood culture practice in a manner that minimizes the impact on patient care.

Identifiers

PMID39810856
PMCPMC11729487

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.