Evidence map›Paper›PMID 39810773›Full record

ArticleKidney international reports2025

Baseline Characteristics of Frailty and Disease Stage in Older People Living With CKD.

Benignus Logan, Elaine M Pascoe, Andrea K Viecelli, David W Johnson, Tracy Comans, Carmel M Hawley, Laura E Hickey, Monika Janda, Allison Jaure, Emarene Kalaw and 14 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Benignus LoganAustralian Frailty Network, The University of Queensland, Brisbane, Australia.
Elaine M PascoeCentre for Health Services Research, The University of Queensland, Brisbane, Australia.
Andrea K ViecelliAustralasian Kidney Trials Network, The University of Queensland, Brisbane, Australia.
David W JohnsonAustralasian Kidney Trials Network, The University of Queensland, Brisbane, Australia.
Tracy ComansAustralian Frailty Network, The University of Queensland, Brisbane, Australia.
Carmel M HawleyAustralasian Kidney Trials Network, The University of Queensland, Brisbane, Australia.
Laura E HickeyAustralasian Kidney Trials Network, The University of Queensland, Brisbane, Australia.
Monika JandaCentre for Health Services Research, The University of Queensland, Brisbane, Australia.
Allison JaureSydney School of Public Health, The University of Sydney, Sydney, Australia.
Emarene KalawAustralasian Kidney Trials Network, The University of Queensland, Brisbane, Australia.
Charani KiriwandeniyaAustralasian Kidney Trials Network, The University of Queensland, Brisbane, Australia.
Misa MatsuyamaAustralasian Kidney Trials Network, The University of Queensland, Brisbane, Australia.
Gabor MihalaCentre for Health Services Research, The University of Queensland, Brisbane, Australia.
Kim-Huong NguyenCentre for Health Services Research, The University of Queensland, Brisbane, Australia.
Jason D PoleCentre for Health Services Research, The University of Queensland, Brisbane, Australia.
Kevan R PolkinghorneSchool of Public Health and Preventive Medicine, Monash University, Melbourne, Australia.
Dimity PondWicking Dementia Research and Education Centre, University of Tasmania, Hobart, Australia.
Rajesh RajSchool of Medicine, University of Tasmania, Hobart, Australia.
Donna M ReidlingerAustralian Frailty Network, The University of Queensland, Brisbane, Australia.
Nicole Scholes-RobertsonSydney School of Public Health, The University of Sydney, Sydney, Australia.
Andrea ValksAustralasian Kidney Trials Network, The University of Queensland, Brisbane, Australia.
Germaine WongSydney School of Public Health, The University of Sydney, Sydney, Australia.
Ruth E HubbardAustralian Frailty Network, The University of Queensland, Brisbane, Australia.
GOAL Trial Investigators

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The GOAL trial, a cluster randomized controlled trial, investigated the effect of comprehensive geriatric assessment (CGA) on frail older people with chronic kidney disease (CKD). This paper describes the following: (i) participant baseline characteristics, and (ii) their relationship with CKD stage and frailty severity. Methods: Sixteen kidney outpatient clinics (clusters) were randomly allocated 1:1 to CGA or usual care. Enrolled frail older people with CKD (Frailty Index [FI] > 0.25; aged ≥65 years or ≥55 if First Nations people) received the intervention allocated to their cluster. CKD was defined as moderate (stages 3 or 4) or severe (stage 5 or 5D), and frailty categorized as moderate (>0.25-<0.36), severe (0.36-<0.45) or very severe (≥0.45). Participant characteristics were analyzed using descriptive statistics. Statistical methods appropriate for type of outcome were used to describe the association of frailty and CKD categories with participant characteristics. Results: Over a 27-month period, 240 people were recruited (55.7% male, 82.9% White/European). Mean age was 76.9 (SD: 6.6) years and median FI was 0.39 (interquartile range [IQR]: 0.32-0.47). The median EQ-5D-5L quality-of-life index score was worse in those with very severe frailty (0.57, IQR: 0.28-0.83) compared to severe frailty (0.85, IQR: 0.67-0.92) and moderate frailty (0.90, IQR: 0.82-0.93) (overall Conclusion: This cohort demonstrated poorer quality-of-life scores in those with more severe frailty and more advanced CKD.

Indexed as

chronic kidney diseasecomprehensive geriatric assessmentfrailtygoal attainment scalingolder peoplequality of life

Identifiers

PMID39810773
PMCPMC11725818

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.