ArticleKidney international reports2025
Association Between Maternal Smoking, Isolated Proteinuria During Pregnancy and Preterm Birth: A Finnish Registry Analysis.
Article in Kidney international reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Introduction: Smoking during pregnancy (SDP) seems to paradoxically decrease the likelihood of preeclampsia. We aimed to investigate the association between smoking and isolated proteinuria during pregnancy. In addition, we investigated the associations and potential interaction between smoking and proteinuria on the risk for preterm birth. Methods: The study included all women with singleton pregnancies ( Results: Of the participants, 14.6% were smokers, of which 36.9% quit smoking; 2534 (0.3%) had a diagnosis of isolated proteinuria. Those who quit smoking (odds ratio [OR] = 1.31, 95% confidence interval [CI] = 1.14-1.52) and those who continued smoking (OR = 1.29, 95% CI=1.15-1.46) were associated with having a diagnosis of isolated proteinuria. Isolated proteinuria (OR = 1.24, 95% CI = 1.03-1.49) and those who continued smoking (OR = 1.45, 95% CI = 1.40-1.50) were associated with preterm birth. The interaction of smoking and isolated proteinuria with preterm birth lacked statistical significance. Conclusion: We found evidence of an association between smoking and the diagnosis of isolated proteinuria. Furthermore, smoking and a diagnosis of isolated proteinuria were both associated with a higher risk for preterm birth.
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