Evidence map›Paper›PMID 39810720›Full record

ReviewHistology and histopathology2025

Testicular cryopreservation: From technical aspects to practical applications.

Ana Glória Pereira, Tayná Moura Matos, Joana Letícia Cottin de Albuquerque, Andréia Maria da Silva, Alexandre Rodrigues Silva

Abstract readReview
PubMed Publisher
In one paragraph

Review in Histology and histopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Biobanking biodiversity: recent strategies, challenges, and opportunities.The Journal of reproduction and development · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ana Glória PereiraLaboratory of Animal Germplasm Conservation, Federal Rural University of the Semiarid Region - UFERSA, Mossoró, RN, Brazil.
Tayná Moura MatosLaboratory of Animal Germplasm Conservation, Federal Rural University of the Semiarid Region - UFERSA, Mossoró, RN, Brazil.
Joana Letícia Cottin de AlbuquerqueLaboratory of Animal Germplasm Conservation, Federal Rural University of the Semiarid Region - UFERSA, Mossoró, RN, Brazil.
Andréia Maria da SilvaLaboratory of Animal Germplasm Conservation, Federal Rural University of the Semiarid Region - UFERSA, Mossoró, RN, Brazil.
Alexandre Rodrigues SilvaLaboratory of Animal Germplasm Conservation, Federal Rural University of the Semiarid Region - UFERSA, Mossoró, RN, Brazil. alexrs@ufersa.edu.br.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Testicular cryopreservation has been highlighted as a promising alternative for preserving male fertility and can be applied to restore spermatogenesis in prepubertal individuals or cancer patients, preserve biologically valuable genotypes, and in studies on reproductive physiology or toxicity of various substances. This review presents an analysis of the technical aspects and applications of testicular cryopreservation, examining the contributions of important studies in this area and discussing the different factors that can impact the efficiency of the technique. Testicular fragments can be obtained from living or dead individuals, at any age and reproductive stage, through orchiectomy or biopsy. Among the methods used for processing, slow freezing and vitrification in open or closed systems stand out. However, factors such as species, age, medium used, cryoprotectants, and cryopreservation method can influence the viability of the testis after heating. To obtain sperm, the testes can be cultured

Indexed as

CryopreservationFertility PreservationTestisAnimalsCryoprotective AgentsHumansMaleSpermatogenesisCryoprotective Agents

Identifiers

PMID39810720

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.